Article(id=1317133112799248611, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.01.007, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791958605240, onlineDateStr=2026-10-14, pubDate=1767974400000, pubDateStr=2026-01-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791958605240, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791958605240, creator=13701087609, updateTime=1791958605240, updator=13701087609, issue=Issue{id=1317133098966433889, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='1', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791958601943, creator='13701087609', updateTime=1791958824557, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317134032719171723, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317134032719171724, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=34, endPage=37, ext={EN=ArticleExt(id=1317133114372112612, articleId=1317133112799248611, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Effects of Yiwei Decoction(益胃汤)and Maimendong Decoction(麦门冬汤)on Clinical Prognosis and Intestinal Flora of Patients with Stomach Stuffiness of Spleen-Stomach Weakness Type(Chronic Gastritis), columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=
Objective

To investigate the effects of Yiwei Decoction(益胃汤)and Maimendong Decoction(麦门冬汤)on the clinical prognosis and intestinal flora of patients with stomach stuffiness of spleen-stomach weakness type.

Methods

A total of 116 patients with stomach stuffiness of spleen-stomach weakness type were selected and randomly divided into control group and observation group,58 cases in each group. The control group was given quadruple therapy,and the observation group was treated with Yiwei Decoction and Maimendong Decoction on the basis of the control group for 4 weeks. Before and after the treatment,the two groups were compared in terms of clinical efficacy,traditional Chinese medicine symptom scores,serum indexes,gastrointestinal hormones,Helicobacter pylori(Hp)conversion and intestinal flora.

Results

After treatment,the total effective rate of the observation group was 94.83%(55/58),which was significantly better than that(79.31%,46/58)of the control group(P<0.05),and the Hp clearance rate of the observation group was 96.55%(56/58),while that the control group was 86.21%(50/58). The traditional Chinese medicine symptom scores of the patients in both groups were significantly reduced(P<0.05),and the scores of the observation group were significantly lower than those of the control group(P<0.05). The levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),transforming growth factor-β1(TGF-β1)and C-reactive protein(CRP)of two groups were significantly lower than those before treatment(P<0.05),and the levels of the observation group were significantly lower than those of the control group(P<0.05). The levels of somatostatin(SS)and epidermal growth factor(EGF)were significantly higher in both groups(P<0.05),and the levels of the observation group were significantly higher than those of the control group(P<0.05). the level of gastrin(GAS)was significantly lower in both groups,and the level of the observation group was significantly lower than that of the control group(P<0.05). Bifidobacterium and Lactobacillus increased in both groups compared with those in the pre-treatment period(P<0.05),and Bifidobacterium and Lactobacillus of the observation group were significantly higher than those of the control group(P<0.05). Staphylococcus and Enterococcus decreased in both groups compared with those in the pre-treatment period(P<0.05),and Staphylococcus and Enterococcus of the observation group were significantly lower than those of the control group(P<0.05).

Conclusion

The clinical efficacy of Yiwei Decoction combined with Maimendong Decoction on patients with stomach stuffiness of spleen-stomach weakness type is remarkable,which can improve the clinical symptoms,reduce the inflammatory reaction and improve the intestinal flora of patients.

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目的

探究益胃汤合麦门冬汤对脾胃虚弱型胃痞患者临床预后及肠道菌群的影响。

方法

选取脾胃虚弱型胃痞患者116例,随机分为对照组及观察组,每组58例。对照组给予四联疗法,观察组在对照组的基础上加用益胃汤合麦门冬汤,疗程4周。分别于治疗前后比较两组患者临床疗效、中医证候评分、血清指标、胃肠激素、幽门螺杆菌(helicobacter pylori,Hp)转阴情况及肠道菌群。

结果

治疗后,观察组总有效率为94.83%(55/58),显著优于对照组(79.31%,46/58)(P<0.05),观察组Hp清除率为96.55%(56/58),对照组Hp清除率为86.21%(50/58);两组患者中医证候评分均显著降低(P<0.05),观察组评分显著低于对照组(P<0.05);两组患者白细胞介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、转化生长因子-β1(transforming growth factor-β1,TGF-β1)、C反应蛋白(C-reactive protein,CRP)均较治疗前显著降低(P<0.05),观察组显著低于对照组(P<0.05);两组患者生长抑素(somatostatin,SS)及表皮生长因子(epidermal growth factor,EGF)均显著升高(P<0.05),且观察组显著高于对照组(P<0.05);两组患者胃泌素(gastrin,GAS)显著降低,且观察组显著低于对照组(P<0.05);两组患者双歧杆菌、乳杆菌较治疗前增加(P<0.05),观察组显著高于对照组(P<0.05);两组患者葡萄球菌及肠球菌较治疗前减少(P<0.05),观察组显著低于对照组(P<0.05)。

结论

益胃汤合麦门冬汤对脾胃虚弱型胃痞患者临床疗效显著,可改善临床症状,减轻炎症反应,改善患者肠道菌群。

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益胃汤合麦门冬汤对脾胃虚弱型胃痞(慢性胃炎)临床预后及肠道菌群的影响
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刘高仁 , 张欣 , 王迎春 , 张勤生
中华中医药学刊 | 国家项目点击 2026,44(1): 34-37
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中华中医药学刊 |国家项目点击 2026 , 44 (1) : 34 -37
益胃汤合麦门冬汤对脾胃虚弱型胃痞(慢性胃炎)临床预后及肠道菌群的影响
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刘高仁, 张欣, 王迎春, 张勤生
作者信息
  • 河南中医药大学第二附属医院,河南郑州 450002
Effects of Yiwei Decoction(益胃汤)and Maimendong Decoction(麦门冬汤)on Clinical Prognosis and Intestinal Flora of Patients with Stomach Stuffiness of Spleen-Stomach Weakness Type(Chronic Gastritis)
Gaoren LIU, Xin ZHANG, Yingchun WANG, Qinsheng ZHANG
Affiliations
  • The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450002, Henan, China
出版时间: 2026-01-10 doi: 10.13193/j.issn.1673-7717.2026.01.007
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目的

探究益胃汤合麦门冬汤对脾胃虚弱型胃痞患者临床预后及肠道菌群的影响。

方法

选取脾胃虚弱型胃痞患者116例,随机分为对照组及观察组,每组58例。对照组给予四联疗法,观察组在对照组的基础上加用益胃汤合麦门冬汤,疗程4周。分别于治疗前后比较两组患者临床疗效、中医证候评分、血清指标、胃肠激素、幽门螺杆菌(helicobacter pylori,Hp)转阴情况及肠道菌群。

结果

治疗后,观察组总有效率为94.83%(55/58),显著优于对照组(79.31%,46/58)(P<0.05),观察组Hp清除率为96.55%(56/58),对照组Hp清除率为86.21%(50/58);两组患者中医证候评分均显著降低(P<0.05),观察组评分显著低于对照组(P<0.05);两组患者白细胞介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、转化生长因子-β1(transforming growth factor-β1,TGF-β1)、C反应蛋白(C-reactive protein,CRP)均较治疗前显著降低(P<0.05),观察组显著低于对照组(P<0.05);两组患者生长抑素(somatostatin,SS)及表皮生长因子(epidermal growth factor,EGF)均显著升高(P<0.05),且观察组显著高于对照组(P<0.05);两组患者胃泌素(gastrin,GAS)显著降低,且观察组显著低于对照组(P<0.05);两组患者双歧杆菌、乳杆菌较治疗前增加(P<0.05),观察组显著高于对照组(P<0.05);两组患者葡萄球菌及肠球菌较治疗前减少(P<0.05),观察组显著低于对照组(P<0.05)。

结论

益胃汤合麦门冬汤对脾胃虚弱型胃痞患者临床疗效显著,可改善临床症状,减轻炎症反应,改善患者肠道菌群。

益胃汤  /  麦门冬汤  /  脾胃虚弱型  /  胃痞  /  肠道菌群
Objective

To investigate the effects of Yiwei Decoction(益胃汤)and Maimendong Decoction(麦门冬汤)on the clinical prognosis and intestinal flora of patients with stomach stuffiness of spleen-stomach weakness type.

Methods

A total of 116 patients with stomach stuffiness of spleen-stomach weakness type were selected and randomly divided into control group and observation group,58 cases in each group. The control group was given quadruple therapy,and the observation group was treated with Yiwei Decoction and Maimendong Decoction on the basis of the control group for 4 weeks. Before and after the treatment,the two groups were compared in terms of clinical efficacy,traditional Chinese medicine symptom scores,serum indexes,gastrointestinal hormones,Helicobacter pylori(Hp)conversion and intestinal flora.

Results

After treatment,the total effective rate of the observation group was 94.83%(55/58),which was significantly better than that(79.31%,46/58)of the control group(P<0.05),and the Hp clearance rate of the observation group was 96.55%(56/58),while that the control group was 86.21%(50/58). The traditional Chinese medicine symptom scores of the patients in both groups were significantly reduced(P<0.05),and the scores of the observation group were significantly lower than those of the control group(P<0.05). The levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),transforming growth factor-β1(TGF-β1)and C-reactive protein(CRP)of two groups were significantly lower than those before treatment(P<0.05),and the levels of the observation group were significantly lower than those of the control group(P<0.05). The levels of somatostatin(SS)and epidermal growth factor(EGF)were significantly higher in both groups(P<0.05),and the levels of the observation group were significantly higher than those of the control group(P<0.05). the level of gastrin(GAS)was significantly lower in both groups,and the level of the observation group was significantly lower than that of the control group(P<0.05). Bifidobacterium and Lactobacillus increased in both groups compared with those in the pre-treatment period(P<0.05),and Bifidobacterium and Lactobacillus of the observation group were significantly higher than those of the control group(P<0.05). Staphylococcus and Enterococcus decreased in both groups compared with those in the pre-treatment period(P<0.05),and Staphylococcus and Enterococcus of the observation group were significantly lower than those of the control group(P<0.05).

Conclusion

The clinical efficacy of Yiwei Decoction combined with Maimendong Decoction on patients with stomach stuffiness of spleen-stomach weakness type is remarkable,which can improve the clinical symptoms,reduce the inflammatory reaction and improve the intestinal flora of patients.

Yiwei Decoction(益胃汤)  /  Maimendong Decoction(麦门冬汤)  /  spleen-stomach weakness type  /  stomach stuffiness  /  intestinal flora
刘高仁, 张欣, 王迎春, 张勤生. 益胃汤合麦门冬汤对脾胃虚弱型胃痞(慢性胃炎)临床预后及肠道菌群的影响. 中华中医药学刊, 2026 , 44 (1) : 34 -37 . DOI: 10.13193/j.issn.1673-7717.2026.01.007
Gaoren LIU, Xin ZHANG, Yingchun WANG, Qinsheng ZHANG. Effects of Yiwei Decoction(益胃汤)and Maimendong Decoction(麦门冬汤)on Clinical Prognosis and Intestinal Flora of Patients with Stomach Stuffiness of Spleen-Stomach Weakness Type(Chronic Gastritis)[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (1) : 34 -37 . DOI: 10.13193/j.issn.1673-7717.2026.01.007

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doi: 10.13193/j.issn.1673-7717.2026.01.007
  • 首发时间:2026-10-14
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    河南中医药大学第二附属医院,河南郑州 450002
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2种不同金属材料的力学参数
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genus
种数
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species
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Percentage of
total species (%)
属
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种数
Number of
species
占总种数比例
Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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