Article(id=1322927687945290312, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322926217711726961, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2025.08.036, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793340139613, onlineDateStr=2026-10-30, pubDate=1754755200000, pubDateStr=2025-08-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793340139613, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793340139613, creator=13701087609, updateTime=1793340139613, updator=13701087609, issue=Issue{id=1322926217711726961, tenantId=1146029695717560320, journalId=1255847919539208197, year='2025', volume='43', issue='8', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1754755200000', pubDateStr='2025-08-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793339789083, creator='13701087609', updateTime=1793340517761, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322929274071679978, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322926217711726961, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322929274071679979, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322926217711726961, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=189, endPage=193, ext={EN=ArticleExt(id=1322927688150811209, articleId=1322927687945290312, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Effect of Xuanfei Huazhuo Formula（宣肺化浊方）on Expressions of CD86 and CD206 in Alveolar Lavage Fluid of Patients with Sepsis Lung Injury with Turbid Toxin Accumulation Syndrome, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the effect of Xuanfei Huazhuo Formula（宣肺化浊方）on the expressions of CD86 and CD206 in alveolar lavage fluid of patients with sepsis lung injury with turbid toxin accumulation syndrome.
Method Sixty patients with sepsis induced lung injury（turbid toxin internal accumulation syndrome）who visited Hebei Provincial Hospital of Traditional Chinese Medicine from September 2022 to September 2023 were selected as the study subjects.The participants were randomly divided into an experimental group and a control group using a random coding table，with 30 cases in each group.The control group were given an equal amount of warm water as a control，while the experimental group were given nasal feeding of Xuanfei Huazhuo Formula on the basis of routine treatment.The total treatment period for both groups was 7 days.The 28-d mortality rate，clinical efficacy，severity of the condition，serum inflammatory response indicators，blood gas indicators，respiratory function indicators and expressions of CD86 and CD206 in alveolar macrophage phenotype in alveolar lavage fluid were compared between two groups.
Result Compared to the control group，the experimental group showed a higher overall effective rate and a lower 28-day mortality rate（P<0.05）.After treatment，the Acute Physiology and Chronic Health Evaluation（APACHE）Ⅱscore and lung injury score（LIS）of both groups decreased（P<0.05），and compared to the control group，the LIS score of the experimental group was lower（P<0.05）.After treatment，the levels of C-reactive protein（CRP），procalcitonin（PCT），interleukin-6（IL-6），tumor necrosis factor-α（TNF-α）and interleukin-10（IL-10）in both groups were reduced（P<0.05），and compared with the control group，the experimental group had lower levels of these indicators（P<0.05）.After treatment，the levels of arterial partial pressure of oxygen（PaO2）and PaO2/FiO2 in both groups increased，while the levels of extravascular lung water index（EVLWI）and pulmonary vascular permeability index（PVPI）decreased（P<0.05）. Compared with the control group，the experimental group performed better on these indicators（P<0.05）.After treatment，the expression of CD68 increased and the expression of CD206 decreased in the alveolar lavage fluid of both groups（P<0.05），and compared to the control group，the experimental group had higher expression of CD68 and lower expression of CD206（P<0.05）.
Conclusion Xuanfei Huazhuo Formula has definite therapeutic effect in treating patients with sepsis induced lung injury due to the accumulation of turbid toxin.Its mechanism of action may be closely related to the regulation of CD86 and CD206 in alveolar lavage fluid，and has clinical application and promotion value.
, authors=Baozhu SHI, Mei XU, Yun GUAN, Jin ZHAO, Tiantian WU, Mingming DUAN, Xuan ZHANG, Yinghao SU, Jie GUO, Yunlei MA, authorsList=Baozhu SHI, Mei XU, Yun GUAN, Jin ZHAO, Tiantian WU, Mingming DUAN, Xuan ZHANG, Yinghao SU, Jie GUO, Yunlei MA, authorCompany=null, correspAuthors=Yunlei MA, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322927689606234710, articleId=1322927687945290312, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=宣肺化浊方对浊毒内蕴证脓毒症肺损伤患者肺泡灌洗液中CD86、CD206表达的影响, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 探讨宣肺化浊方对浊毒内蕴证脓毒症肺损伤患者肺泡灌洗液中CD86、CD206表达的影响。
方法 选择于2022年9月—2023年9月来河北省中医院就诊的脓毒症肺损伤（浊毒内蕴证）患者60例作为研究对象，采用随机编码表将入选者分成试验组及对照组，每组30例。对照组以等量温开水对照，试验组在常规治疗基础上给予宣肺化浊汤鼻饲。两组患者总疗程均为7 d。对比两组28 d病死率、临床疗效、病情严重程度、血清炎症反应指标、血气指标、呼吸功能指标、肺泡灌洗液中肺泡巨噬细胞表型CD86和CD206表达情况。
结果 相较于对照组，试验组总有效率较高，28 d病死率较低（P<0.05）。治疗后，两组患者的急性生理与慢性健康评分（APACHE II评分）和肺损伤评分（LIS评分）均有所下降（P<0.05），且相较于对照组，试验组的肺损伤LIS评分更低（P<0.05）。治疗后，两组患者的C反应蛋白（CRP）、降钙素原（PCT）、白细胞介素（IL）-6、肿瘤坏死因子-α（TNF-α）以及IL-10水平均有所降低（P<0.05），与对照组相比，试验组的这些指标水平更低（P<0.05）。治疗后，两组患者的动脉血氧分压（PaO2）和氧合指数（PaO2/FiO2）水平有所上升，血管外肺水指数（EVLWI）及肺血管通透指数（PVPI）水平有所下降（P<0.05），且相较于对照组，试验组在这些指标上表现更好（P<0.05）。治疗后，两组患者的肺泡灌洗液中CD68表达上升，CD206表达下降（P<0.05），且相较于对照组，试验组的CD68表达更高，CD206表达更低（P<0.05）。
结论 宣肺化浊方在治疗浊毒内蕴证脓毒症肺损伤患者方面表现出确切的疗效，其作用机制可能与调控肺泡灌洗液中CD86、CD206水平密切相关，具备临床应用和推广的价值。
, authors=施保柱, 许梅, 观云, 赵津, 吴甜甜, 段明明, 张萱, 宿英豪, 郭洁, 马蕴蕾, authorsList=施保柱, 许梅, 观云, 赵津, 吴甜甜, 段明明, 张萱, 宿英豪, 郭洁, 马蕴蕾, authorCompany=null, correspAuthors=马蕴蕾, authorNote=
施保柱（1979-），男（满族），河北承德人，副主任医师，学士，研究方向：呼吸重症。
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施保柱（1979-），男（满族），河北承德人，副主任医师，学士，研究方向：呼吸重症。
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施保柱（1979-），男（满族），河北承德人，副主任医师，学士，研究方向：呼吸重症。
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journalId=1255847919539208197, articleId=1322927687945290312, language=CN, orderNo=4, keyword=肺泡灌洗液), Keyword(id=1322927698703680152, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, language=CN, orderNo=5, keyword=CD86), Keyword(id=1322927698959532698, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, language=CN, orderNo=6, keyword=CD206)], refs=[Reference(id=1322927702226895529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=51, issue=3, pageStart=333, pageEnd=336, url=null, language=null, rfNumber=［1］, rfOrder=0, authorNames=胡英山, 王晶晶, 高红梅, journalName=天津医药, refType=null, unstructuredReference=胡英山，王晶晶，高红梅. 脓毒症相关肠道功能障碍发病机制的研究进展［J］.
天津医药，
2023，
51（3）：333-336., articleTitle=脓毒症相关肠道功能障碍发病机制的研究进展, refAbstract=null), Reference(id=1322927702306587306, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=27, issue=1, pageStart=37, pageEnd=40, url=null, language=null, rfNumber=［2］, rfOrder=1, authorNames=封慧, 李琴, 李思睿, journalName=中国实验诊断学, refType=null, unstructuredReference=封慧，李琴，李思睿. 脓毒症休克患者动脉血乳酸、血清白蛋白比值在预测病情评估及转归的临床价值［J］.
中国实验诊断学，
2023，
27（1）：37-40., articleTitle=脓毒症休克患者动脉血乳酸、血清白蛋白比值在预测病情评估及转归的临床价值, refAbstract=null), Reference(id=1322927702377890475, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=43, issue=4, pageStart=296, pageEnd=300, url=null, language=null, rfNumber=［3］, rfOrder=2, authorNames=张志斌, 王楚, 韩英, journalName=中国急救医学, refType=null, unstructuredReference=张志斌，王楚，韩英，
等. 白血病抑制因子及受激活调节正常T细胞表达和分泌因子对血流感染脓毒症患者的诊断及预后评估价值［J］.
中国急救医学，
2023，
43（4）：296-300., articleTitle=白血病抑制因子及受激活调节正常T细胞表达和分泌因子对血流感染脓毒症患者的诊断及预后评估价值, refAbstract=null), Reference(id=1322927702457582252, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2021, volume=50, issue=8, pageStart=1385, pageEnd=1388, url=null, language=null, rfNumber=［4］, rfOrder=3, authorNames=甘伟忠, 卢彩宝, 李芙蓉, journalName=重庆医学, refType=null, unstructuredReference=甘伟忠，卢彩宝，李芙蓉，
等. 介入时机对CRRT治疗脓毒症致AKI的疗效影响［J］.
重庆医学，
2021，
50（8）：1385-1388., articleTitle=介入时机对CRRT治疗脓毒症致AKI的疗效影响, refAbstract=null), Reference(id=1322927702537274029, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=29, issue=5, pageStart=573, pageEnd=578, url=null, language=null, rfNumber=［5］, rfOrder=4, authorNames=余剑波, 史佳, journalName=中国中西医结合外科杂志, refType=null, unstructuredReference=余剑波，史佳. 脓毒症急性肺损伤的中西医结合治疗概述［J］.
中国中西医结合外科杂志，
2023，
29（5）：573-578., articleTitle=脓毒症急性肺损伤的中西医结合治疗概述, refAbstract=null), Reference(id=1322927702616965806, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=43, issue=7, pageStart=1336, pageEnd=1342, url=null, language=null, rfNumber=［6］, rfOrder=5, authorNames=丛迪迪, 梁群, 付晨菲, journalName=湖南中医药大学学报, refType=null, unstructuredReference=丛迪迪，梁群，付晨菲，
等. 中医药多靶点干预脓毒症急性肺损伤机制研究概述［J］.
湖南中医药大学学报，
2023，
43（7）：1336-1342., articleTitle=中医药多靶点干预脓毒症急性肺损伤机制研究概述, refAbstract=null), Reference(id=1322927702717629103, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2021, volume=null, issue=10, pageStart=1159, pageEnd=1164, url=null, language=null, rfNumber=［7］, rfOrder=6, authorNames=郑瑞强, 张艺芬, 荣子琪, journalName=中华危重病急救医学, refType=null, unstructuredReference=郑瑞强，张艺芬，荣子琪，
等. 《拯救脓毒症运动：脓毒症与感染性休克治疗国际指南2021版》解读与展望［J］.
中华危重病急救医学，
2021（10）：1159-1164., articleTitle=《拯救脓毒症运动：脓毒症与感染性休克治疗国际指南2021版》解读与展望, refAbstract=null), Reference(id=1322927702797320880, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=1994, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［8］, rfOrder=7, authorNames=国家中医药管理局, journalName=null, refType=null, unstructuredReference=国家中医药管理局. 中医病证诊断疗效标准［S］. 南京：南京大学出版社，
1994., articleTitle=null, refAbstract=null), Reference(id=1322927702868624049, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2019, volume=27, issue=5, pageStart=32, pageEnd=41, url=null, language=null, rfNumber=［9］, rfOrder=8, authorNames=HUNT A, journalName=Emerg Nurse, refType=null, unstructuredReference=HUNT A. Sepsis：an overview of the signs，symptoms，diagnosis，treatment and pathophysiology［J］.
Emerg Nurse，
2019，
27（5）：32-41., articleTitle=Sepsis：an overview of the signs，symptoms，diagnosis，treatment and pathophysiology, refAbstract=null), Reference(id=1322927702948315826, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2019, volume=52, issue=4, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［10］, rfOrder=9, authorNames=SALOMÃO R, FERREIRA B L, SALOMÃOM C, journalName=Braz J Med Biol Res, refType=null, unstructuredReference=SALOMÃO R，FERREIRA B L，SALOMÃOM C，
et al. Sepsis：evolving concepts and challenges［J］.
Braz J Med Biol Res，
2019，
52（4）：e8595., articleTitle=Sepsis：evolving concepts and challenges, refAbstract=null), Reference(id=1322927703028007603, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2022, volume=79, issue=6, pageStart=424, pageEnd=436, url=null, language=null, rfNumber=［11］, rfOrder=10, authorNames=JACOBI J, journalName=Am J Health Syst Pharm, refType=null, unstructuredReference=JACOBI J. The pathophysiology of sepsis—2021 update：part 2，organ dysfunction and assessment［J］.
Am J Health Syst Pharm，
2022，
79（6）：424-436., articleTitle=The pathophysiology of sepsis—2021 update：part 2，organ dysfunction and assessment, refAbstract=null), Reference(id=1322927703107699380, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2020, volume=29, issue=21, pageStart=1248, pageEnd=1251, url=null, language=null, rfNumber=［12］, rfOrder=11, authorNames=BLEAKLEY G, COLE M, journalName=Br J Nurs, refType=null, unstructuredReference=BLEAKLEY G，COLE M. Recognition and management of sepsis：the nurse’s role［J］.
Br J Nurs，
2020，
29（21）：1248-1251., articleTitle=Recognition and management of sepsis：the nurse’s role, refAbstract=null), Reference(id=1322927703174808245, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=35, issue=8, pageStart=884, pageEnd=888, url=null, language=null, rfNumber=［13］, rfOrder=12, authorNames=俞典, 谢永鹏, 李小民, journalName=中华危重病急救医学, refType=null, unstructuredReference=俞典，谢永鹏，李小民. 基于Hippo信号通路探究自噬在脓毒症ARDS肺损伤中的作用机制［J］.
中华危重病急救医学，
2023，
35（8）：884-888., articleTitle=基于Hippo信号通路探究自噬在脓毒症ARDS肺损伤中的作用机制, refAbstract=null), Reference(id=1322927703241917110, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2021, volume=33, issue=5, pageStart=523, pageEnd=528, url=null, language=null, rfNumber=［14］, rfOrder=13, authorNames=李娜, 朱雄, 程远, journalName=中华危重病急救医学, refType=null, unstructuredReference=李娜，朱雄，程远，
等. MLKL-NLRP3炎症小体介导的坏死性炎症反应在脓毒症急性肺损伤小鼠中的作用及其机制［J］.
中华危重病急救医学，
2021，
33（5）：523-528., articleTitle=MLKL-NLRP3炎症小体介导的坏死性炎症反应在脓毒症急性肺损伤小鼠中的作用及其机制, refAbstract=null), Reference(id=1322927703309025975, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2011, volume=null, issue=4, pageStart=253, pageEnd=254，I0003, url=null, language=null, rfNumber=［15］, rfOrder=14, authorNames=朱虹, 蔡佩佩, 尹小燕, journalName=中国危重病急救医学, refType=null, unstructuredReference=朱虹，蔡佩佩，尹小燕，
等. 高迁移率族蛋白B1在脓毒症大鼠急性肺损伤中的作用［J］.
中国危重病急救医学，
2011（4）：253-254，I0003., articleTitle=高迁移率族蛋白B1在脓毒症大鼠急性肺损伤中的作用, refAbstract=null), Reference(id=1322927703380329144, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=18, issue=8, pageStart=1046, pageEnd=1050, url=null, language=null, rfNumber=［16］, rfOrder=15, authorNames=刘文悦, 王丽晖, 卢清龙, journalName=中国急救复苏与灾害医学杂志, refType=null, unstructuredReference=刘文悦，王丽晖，卢清龙. 动态监测脓毒症患者肠道菌群变化与危险分层及预后的关系［J］.
中国急救复苏与灾害医学杂志，
2023，
18（8）：1046-1050., articleTitle=动态监测脓毒症患者肠道菌群变化与危险分层及预后的关系, refAbstract=null), Reference(id=1322927703460020921, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2022, volume=48, issue=3, pageStart=825, pageEnd=831, url=null, language=null, rfNumber=［17］, rfOrder=16, authorNames=蒋孙班, 康思思, 赵利娜, journalName=吉林大学学报（医学版）, refType=null, unstructuredReference=蒋孙班，康思思，赵利娜，
等. TLRs信号通路和TLRs的Cross-talk在炎症性疾病中作用的研究进展［J］.
吉林大学学报（医学版），
2022，
48（3）：825-831., articleTitle=TLRs信号通路和TLRs的Cross-talk在炎症性疾病中作用的研究进展, refAbstract=null), Reference(id=1322927703527129786, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2022, volume=31, issue=3, pageStart=443, pageEnd=446, url=null, language=null, rfNumber=［18］, rfOrder=17, authorNames=李岩, 唐婷婷, 耿艳, journalName=中国中医急症, refType=null, unstructuredReference=李岩，唐婷婷，耿艳. 大承气汤联合基础治疗对脓毒症肺损伤患者炎症指标和预后的影响［J］.
中国中医急症，
2022，
31（3）：443-446., articleTitle=大承气汤联合基础治疗对脓毒症肺损伤患者炎症指标和预后的影响, refAbstract=null), Reference(id=1322927703627793083, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=23, issue=1, pageStart=120, pageEnd=122，128, url=null, language=null, rfNumber=［19］, rfOrder=18, authorNames=侯一楠, 梁群, 杨俊, journalName=中国医院用药评价与分析, refType=null, unstructuredReference=侯一楠，梁群，杨俊，
等. 中药注射剂和中药提取物治疗脓毒症急性肺损伤的研究进展［J］.
中国医院用药评价与分析，
2023，
23（1）：120-122，128., articleTitle=中药注射剂和中药提取物治疗脓毒症急性肺损伤的研究进展, refAbstract=null), Reference(id=1322927703690707644, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=44, issue=1, pageStart=45, pageEnd=49，59, url=null, language=null, rfNumber=［20］, rfOrder=19, authorNames=刁冰冰, 梁群, journalName=陕西中医, refType=null, unstructuredReference=刁冰冰，梁群. 化纤胶囊Ⅱ号方治疗脓毒症急性肺损伤疗效及对患者血管内皮细胞功能、毛细血管渗漏指数的影响［J］.
陕西中医，
2023，
44（1）：45-49，59., articleTitle=化纤胶囊Ⅱ号方治疗脓毒症急性肺损伤疗效及对患者血管内皮细胞功能、毛细血管渗漏指数的影响, refAbstract=null), Reference(id=1322927703762010813, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=41, issue=2, pageStart=94, pageEnd=103, url=null, language=null, rfNumber=［21］, rfOrder=20, authorNames=黄蕊, 何文菊, 张平平, journalName=中华劳动卫生职业病杂志, refType=null, unstructuredReference=黄蕊，何文菊，张平平，
等. 基于网络药理学和整体动物实验探讨凉膈散通过ERK1/2与PI3K/AKT通路治疗脓毒症急性肺损伤［J］.
中华劳动卫生职业病杂志，
2023，
41（2）：94-103., articleTitle=基于网络药理学和整体动物实验探讨凉膈散通过ERK1/2与PI3K/AKT通路治疗脓毒症急性肺损伤, refAbstract=null), Reference(id=1322927705406177982, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2022, volume=38, issue=6, pageStart=13, pageEnd=20, url=null, language=null, rfNumber=［22］, rfOrder=21, authorNames=贺燕玲, 毛祥正, 李莎, journalName=中药药理与临床, refType=null, unstructuredReference=贺燕玲，毛祥正，李莎，
等. 基于网络药理学探讨清瘟败毒饮治疗脓毒症急性肺损伤的机制研究［J］.
中药药理与临床，
2022，
38（6）：13-20., articleTitle=基于网络药理学探讨清瘟败毒饮治疗脓毒症急性肺损伤的机制研究, refAbstract=null), Reference(id=1322927705477481151, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=42, issue=1, pageStart=64, pageEnd=71, url=null, language=null, rfNumber=［23］, rfOrder=22, authorNames=翟延评, 何耀军, 潘嘉宇, journalName=东南大学学报（医学版）, refType=null, unstructuredReference=翟延评，何耀军，潘嘉宇，
等. Casp-8通过调控NLRP3炎性小体介导的细胞焦亡减轻脓毒症引起的急性肺损伤［J］.
东南大学学报（医学版），
2023，
42（1）：64-71., articleTitle=Casp-8通过调控NLRP3炎性小体介导的细胞焦亡减轻脓毒症引起的急性肺损伤, refAbstract=null), Reference(id=1322927705552978624, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=40, issue=5, pageStart=1214, pageEnd=1220, url=null, language=null, rfNumber=［24］, rfOrder=23, authorNames=薛涵予, 王泽秀, 张晓丽, journalName=广州中医药大学学报, refType=null, unstructuredReference=薛涵予，王泽秀，张晓丽. 橙花叔醇对脓毒症急性肺损伤大鼠炎症反应及AMPK/SIRT1通路的影响［J］.
广州中医药大学学报，
2023，
40（5）：1214-1220., articleTitle=橙花叔醇对脓毒症急性肺损伤大鼠炎症反应及AMPK/SIRT1通路的影响, refAbstract=null), Reference(id=1322927705641059009, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2020, volume=30, issue=12, pageStart=9, pageEnd=16, url=null, language=null, rfNumber=［25］, rfOrder=24, authorNames=黄钟, 孙洁, 姚振滨, journalName=中国比较医学杂志, refType=null, unstructuredReference=黄钟，孙洁，姚振滨，
等. 下调miR-128-3p缓解脓毒症大鼠急性肺损伤的炎症反应和肺组织形态学的影响［J］.
中国比较医学杂志，
2020，
30（12）：9-16., articleTitle=下调miR-128-3p缓解脓毒症大鼠急性肺损伤的炎症反应和肺组织形态学的影响, refAbstract=null), Reference(id=1322927705708167874, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2022, volume=29, issue=4, pageStart=412, pageEnd=416, url=null, language=null, rfNumber=［26］, rfOrder=25, authorNames=李珊, 王艳玲, 黄冬林, journalName=中国中西医结合急救杂志, refType=null, unstructuredReference=李珊，王艳玲，黄冬林，
等. 血必净通过调控自噬减轻脓毒症炎症反应和肺损伤的实验研究［J］.
中国中西医结合急救杂志，
2022，
29（4）：412-416., articleTitle=血必净通过调控自噬减轻脓毒症炎症反应和肺损伤的实验研究, refAbstract=null), Reference(id=1322927705779471043, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2020, volume=39, issue=6, pageStart=57, pageEnd=62, url=null, language=null, rfNumber=［27］, rfOrder=26, authorNames=钟春蕾, 黄国涛, 张志强, journalName=安徽中医药大学学报, refType=null, unstructuredReference=钟春蕾，黄国涛，张志强. 五味子乙素对脂多糖诱导的脓毒症急性肺损伤大鼠肺组织病理损伤、炎症反应和核因子-κB表达的影响［J］.
安徽中医药大学学报，
2020，
39（6）：57-62., articleTitle=五味子乙素对脂多糖诱导的脓毒症急性肺损伤大鼠肺组织病理损伤、炎症反应和核因子-κB表达的影响, refAbstract=null), Reference(id=1322927705846579908, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2019, volume=12, issue=3, pageStart=145, pageEnd=151, url=null, language=null, rfNumber=［28］, rfOrder=27, authorNames=徐桂萍, 李青青, 张宇轩, journalName=中华危重症医学杂志（电子版）, refType=null, unstructuredReference=徐桂萍，李青青，张宇轩，
等. 持续静脉泵注利多卡因对脓毒症大鼠急性肺损伤及炎症反应的影响［J/OL］.
中华危重症医学杂志（电子版），
2019，
12（3）：145-151., articleTitle=持续静脉泵注利多卡因对脓毒症大鼠急性肺损伤及炎症反应的影响, refAbstract=null), Reference(id=1322927705917883077, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=39, issue=6, pageStart=1014, pageEnd=1020, url=null, language=null, rfNumber=［29］, rfOrder=28, authorNames=胡军峰, 聂颖, 徐辉甫, journalName=中国病理生理杂志, refType=null, unstructuredReference=胡军峰，聂颖，徐辉甫. 芒果苷通过抑制炎症、肺泡化阻滞和肺微血管受损来减轻高氧诱导的新生小鼠肺损伤［J］.
中国病理生理杂志，
2023，
39（6）：1014-1020., articleTitle=芒果苷通过抑制炎症、肺泡化阻滞和肺微血管受损来减轻高氧诱导的新生小鼠肺损伤, refAbstract=null), Reference(id=1322927705980797638, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=45, issue=18, pageStart=1910, pageEnd=1914，1920，2017, url=null, language=null, rfNumber=［30］, rfOrder=29, authorNames=韩杨杨, 张益维, 应静, journalName=浙江医学, refType=null, unstructuredReference=韩杨杨，张益维，应静，
等. 右美托咪定对脂多糖致小鼠急性肺损伤及肺泡巨噬细胞自噬的影响［J］.
浙江医学，
2023，
45（18）：1910-1914，1920，2017., articleTitle=右美托咪定对脂多糖致小鼠急性肺损伤及肺泡巨噬细胞自噬的影响, refAbstract=null), Reference(id=1322927706052100807, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2022, volume=13, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［31］, rfOrder=30, authorNames=CUTOLO M, CAMPITIELLO R, GOTELLI E, journalName=Front Immunol, refType=null, unstructuredReference=CUTOLO M，CAMPITIELLO R，GOTELLI E，
et al. The role of M1/M2 macrophage polarization in rheumatoid arthritis synovitis［J］.
Front Immunol，
2022，
13：867260., articleTitle=The role of M1/M2 macrophage polarization in rheumatoid arthritis synovitis, refAbstract=null), Reference(id=1322927706127598280, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=12, issue=7, pageStart=1047, pageEnd=null, url=null, language=null, rfNumber=［32］, rfOrder=31, authorNames=CORTÉS-MORALESV A, CHÁVEZ-SÁNCHEZ L, ROCHAZAVALETA L, journalName=Cells, refType=null, unstructuredReference=CORTÉS-MORALESV A，CHÁVEZ-SÁNCHEZ L，ROCHAZAVALETA L，
et al. Mesenchymal stem/stromal cells derived from cervical cancer promote M2 macrophage polarization［J］.
Cells，
2023，
12（7）：1047., articleTitle=Mesenchymal stem/stromal cells derived from cervical cancer promote M2 macrophage polarization, refAbstract=null), Reference(id=1322927706194707145, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=2023, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［33］, rfOrder=32, authorNames=HASTINGS C J, HIMMLER G E, PATEL A, journalName=bioRxiv, refType=null, unstructuredReference=HASTINGS C J，HIMMLER G E，PATEL A，
et al. Immune response modulation by
Pseudomonas aeruginosa persister cells［J］.
bioRxiv，
2023，
2023：523056., articleTitle=Immune response modulation by
Pseudomonas aeruginosa persister cells, refAbstract=null), Reference(id=1322927706270204618, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2023, volume=13, issue=1, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［34］, rfOrder=33, authorNames=XU Y, HU K, LIU C Y, journalName=Sci Rep, refType=null, unstructuredReference=XU Y，HU K，LIU C Y，
et al. Eschar dissolution and the immunoregulator effect of keratinase on burn wounds［J］.
Sci Rep，
2023，
13（1）：13238., articleTitle=Eschar dissolution and the immunoregulator effect of keratinase on burn wounds, refAbstract=null), Reference(id=1322927706467336907, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2022, volume=37, issue=22, pageStart=4200, pageEnd=4203, url=null, language=null, rfNumber=［35］, rfOrder=34, authorNames=王书平, 王东芳, journalName=中国妇幼保健, refType=null, unstructuredReference=王书平，王东芳. 肺泡灌洗液细胞成分血清超敏C-反应蛋白及CD64联合检测在社区获得性肺炎患儿诊断和病情评价中的作用［J］.
中国妇幼保健，
2022，
37（22）：4200-4203., articleTitle=肺泡灌洗液细胞成分血清超敏C-反应蛋白及CD64联合检测在社区获得性肺炎患儿诊断和病情评价中的作用, refAbstract=null), Reference(id=1322927706530251468, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2021, volume=37, issue=5, pageStart=404, pageEnd=409, url=null, language=null, rfNumber=［36］, rfOrder=35, authorNames=王志强, 常克, 曾靖雯, journalName=免疫学杂志, refType=null, unstructuredReference=王志强，常克，曾靖雯，
等. 紫草素调节新生小鼠缺氧诱导的肺损伤和肺泡巨噬细胞中M1/M2型极化及炎性因子水平［J］.
免疫学杂志，
2021，
37（5）：404-409., articleTitle=紫草素调节新生小鼠缺氧诱导的肺损伤和肺泡巨噬细胞中M1/M2型极化及炎性因子水平, refAbstract=null), Reference(id=1322927706601554637, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2021, volume=62, issue=23, pageStart=2084, pageEnd=2091, url=null, language=null, rfNumber=［37］, rfOrder=36, authorNames=武颖烁, 尚艺婉, 孟丹华, journalName=中医杂志, refType=null, unstructuredReference=武颖烁，尚艺婉，孟丹华，
等. 补肺益肾方对慢性阻塞性肺疾病模型小鼠肺泡巨噬细胞胞葬功能及PPARγ通路的影响［J］.
中医杂志，
2021，
62（23）：2084-2091., articleTitle=补肺益肾方对慢性阻塞性肺疾病模型小鼠肺泡巨噬细胞胞葬功能及PPARγ通路的影响, refAbstract=null), Reference(id=1322927706664469198, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, doi=null, pmid=null, pmcid=null, year=2022, volume=40, issue=1, pageStart=44, pageEnd=48, url=null, language=null, rfNumber=［38］, rfOrder=37, authorNames=李旭炯, 张慧英, 陈云霞, journalName=中国临床解剖学杂志, refType=null, unstructuredReference=李旭炯，张慧英，陈云霞，
等. 肝肺综合征大鼠模型肺组织巨噬细胞表型变化［J］.
中国临床解剖学杂志，
2022，
40（1）：44-48., articleTitle=肝肺综合征大鼠模型肺组织巨噬细胞表型变化, refAbstract=null)], funds=[Fund(id=1322927702054929063, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, awardId=ZF2024158, language=CN, fundingSource=河北省卫生健康委政府资助临床医学优秀人才培养项目(ZF2024158), fundOrder=null, country=null), Fund(id=1322927702126232232, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, awardId=2024007, language=CN, fundingSource=河北省中医药管理局科研计划项目(2024007), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1322927689836921431, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, xref=null, ext=[AuthorCompanyExt(id=1322927689849504344, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, companyId=1322927689836921431, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Hebei Provincial Hospital of Traditional Chinese Medicine，Shijiazhuang 050000，Hebei，China), AuthorCompanyExt(id=1322927689857892953, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, companyId=1322927689836921431, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=河北省中医院，河北 石家庄 050000)])], figs=[ArticleFig(id=1322927699081167515, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 男/女 | 年龄/（岁） | 发病时间/（h） | 原发病/［例（%）］ |
|---|
| 泌尿系统感染 | 消化系统感染 | 呼吸系统感染 |
|---|
| 试验组 | 30 | 19/11 | 60.20±6.53 | 22.43±2.54 | 10（33.33） | 8（26.67） | 12（40.00） |
| 对照组 | 30 | 18/12 | 60.18±6.60 | 22.50±2.56 | 9（30.00） | 7（23.33） | 14（46.67） |
), ArticleFig(id=1322927699152470684, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, language=CN, label=表1, caption=
两组脓毒症肺损伤（浊毒内蕴证）患者一般情况比较（
）
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| 组别 | 例数 | 男/女 | 年龄/（岁） | 发病时间/（h） | 原发病/［例（%）］ |
|---|
| 泌尿系统感染 | 消化系统感染 | 呼吸系统感染 |
|---|
| 试验组 | 30 | 19/11 | 60.20±6.53 | 22.43±2.54 | 10（33.33） | 8（26.67） | 12（40.00） |
| 对照组 | 30 | 18/12 | 60.18±6.60 | 22.50±2.56 | 9（30.00） | 7（23.33） | 14（46.67） |
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| 组别 | 例数 | 临床控制 | 有效 | 无效 | 总有效 | 28 d 病死率 |
|---|
| 试验组 | 30 | 7（23.33） | 19（63.33） | 4（13.33） | 26（86.67）* | 2（6.67）* |
| 对照组 | 30 | 5（16.67） | 12（40.00） | 13（43.33） | 17（56.67） | 10（33.33） |
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两组脓毒症肺损伤（浊毒内蕴证）患者临床疗效比较
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| 组别 | 例数 | 临床控制 | 有效 | 无效 | 总有效 | 28 d 病死率 |
|---|
| 试验组 | 30 | 7（23.33） | 19（63.33） | 4（13.33） | 26（86.67）* | 2（6.67）* |
| 对照组 | 30 | 5（16.67） | 12（40.00） | 13（43.33） | 17（56.67） | 10（33.33） |
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| 组别 | 例数 | 时间 | APACHEII | 肺损伤LIS 评分 |
|---|
| 试验组 | 30 | 治疗前 | 24.33±3.15 | 2.45±0.36 |
| | 治疗后 | 14.30±1.54*# | 0.89±0.14*# |
| 对照组 | 30 | 治疗前 | 24.50±3.14 | 2.44±0.35 |
| | 治疗后 | 19.60±1.33* | 1.34±0.25* |
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两组脓毒症肺损伤（浊毒内蕴证）患者病情严重程度比较（
）
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| 组别 | 例数 | 时间 | APACHEII | 肺损伤LIS 评分 |
|---|
| 试验组 | 30 | 治疗前 | 24.33±3.15 | 2.45±0.36 |
| | 治疗后 | 14.30±1.54*# | 0.89±0.14*# |
| 对照组 | 30 | 治疗前 | 24.50±3.14 | 2.44±0.35 |
| | 治疗后 | 19.60±1.33* | 1.34±0.25* |
), ArticleFig(id=1322927701526446753, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 时间 | CRP/（mg/dL） | PCT/（ng/mL） | IL-6/（pg/mL） | TNF-α/（ng/L） | IL-10/（pg/mL） |
|---|
| 试验组 | 30 | 治疗前 | 20.35±3.83 | 10.24±1.43 | 29.32±3.44 | 1 543.43±203.22 | 94.24±10.32 |
| | 治疗后 | 8.34±0.92*# | 2.34±0.43*# | 18.23±2.32*# | 781.32±88.33*# | 78.13±8.44*# |
| 对照组 | 30 | 治疗前 | 20.55±3.79 | 10.19±1.45 | 29.28±3.50 | 1 540.50±201.32 | 94.03±10.35 |
| | 治疗后 | 13.54±1.66* | 5.42±0.65* | 24.35±2.89* | 1 111.49±134.52* | 82.33±9.43* |
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两组脓毒症肺损伤（浊毒内蕴证）患者炎症反应比较（
）
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| 组别 | 例数 | 时间 | CRP/（mg/dL） | PCT/（ng/mL） | IL-6/（pg/mL） | TNF-α/（ng/L） | IL-10/（pg/mL） |
|---|
| 试验组 | 30 | 治疗前 | 20.35±3.83 | 10.24±1.43 | 29.32±3.44 | 1 543.43±203.22 | 94.24±10.32 |
| | 治疗后 | 8.34±0.92*# | 2.34±0.43*# | 18.23±2.32*# | 781.32±88.33*# | 78.13±8.44*# |
| 对照组 | 30 | 治疗前 | 20.55±3.79 | 10.19±1.45 | 29.28±3.50 | 1 540.50±201.32 | 94.03±10.35 |
| | 治疗后 | 13.54±1.66* | 5.42±0.65* | 24.35±2.89* | 1 111.49±134.52* | 82.33±9.43* |
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| 组别 | 例数 | 时间 | PaO2/（mmHg） | PaO2/FiO2/（mmHg） | EVLWI/（mL/kg） | PVPI/（%） |
|---|
| 试验组 | 30 | 治疗前 | 60.34±6.66 | 253.43±36.44 | 14.55±1.65 | 3.82±0.46 |
| | 治疗后 | 89.23±9.42*# | 388.54±43.54*# | 7.03±0.82*# | 1.53±0.21*# |
| 对照组 | 30 | 治疗前 | 60.50±6.70 | 253.40±36.50 | 14.50±1.70 | 3.90±0.45 |
| | 治疗后 | 78.23±8.43* | 340.21±40.12* | 9.22±1.02* | 2.25±0.31* |
), ArticleFig(id=1322927701773910692, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, language=CN, label=表5, caption=
两组脓毒症肺损伤（浊毒内蕴证）患者血气指标及呼吸功能指标比较（
）
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 时间 | PaO2/（mmHg） | PaO2/FiO2/（mmHg） | EVLWI/（mL/kg） | PVPI/（%） |
|---|
| 试验组 | 30 | 治疗前 | 60.34±6.66 | 253.43±36.44 | 14.55±1.65 | 3.82±0.46 |
| | 治疗后 | 89.23±9.42*# | 388.54±43.54*# | 7.03±0.82*# | 1.53±0.21*# |
| 对照组 | 30 | 治疗前 | 60.50±6.70 | 253.40±36.50 | 14.50±1.70 | 3.90±0.45 |
| | 治疗后 | 78.23±8.43* | 340.21±40.12* | 9.22±1.02* | 2.25±0.31* |
), ArticleFig(id=1322927701849408165, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 时间 | CD86 | CD206 |
|---|
| 试验组 | 30 | 治疗前 | 5.35±0.64 | 0.92±0.10 |
| | 治疗后 | 2.32±0.25*# | 2.12±0.25*# |
| 对照组 | 30 | 治疗前 | 5.40±0.66 | 0.95±0.11 |
| | 治疗后 | 3.21±0.42* | 1.29±0.18* |
), ArticleFig(id=1322927701920711334, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322927687945290312, language=CN, label=表6, caption=
两组脓毒症肺损伤（浊毒内蕴证）患者肺泡灌洗液中CD86、CD206表达对比（
）
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| 组别 | 例数 | 时间 | CD86 | CD206 |
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| 试验组 | 30 | 治疗前 | 5.35±0.64 | 0.92±0.10 |
| | 治疗后 | 2.32±0.25*# | 2.12±0.25*# |
| 对照组 | 30 | 治疗前 | 5.40±0.66 | 0.95±0.11 |
| | 治疗后 | 3.21±0.42* | 1.29±0.18* |
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