Article(id=1322926134811308863, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322925862630339452, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2025.07.040, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793339769318, onlineDateStr=2026-10-30, pubDate=1752076800000, pubDateStr=2025-07-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793339769318, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793339769317, creator=13701087609, updateTime=1793339769317, updator=13701087609, issue=Issue{id=1322925862630339452, tenantId=1146029695717560320, journalId=1255847919539208197, year='2025', volume='43', issue='7', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1752076800000', pubDateStr='2025-07-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793339704424, creator='13701087609', updateTime=1793340532184, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322929334587105328, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322925862630339452, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322929334587105329, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322925862630339452, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=204, endPage=207, ext={EN=ArticleExt(id=1322926135004246848, articleId=1322926134811308863, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Application of Guizhi Longgu Muli Decoction（桂枝龙骨牡蛎汤）Combined with Repetitive Transcranial Magnetic Stimulation in Chronic Obstructive Pulmonary Disease with Anxiety and Depression, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To evaluate the application of Guizhi Longgu Muli Decoction（桂枝龙骨牡蛎汤）combined with repetitive transcranial magnetic stimulation in chronic obstructive pulmonary disease（COPD）with anxiety and depression.
Method A prospective study was conducted to select 98 COPD patients with anxiety and depression who received a systematic diagnosis and treatment plan，and to cooperate in completing the follow-up process. According to the random number table method，the patients were divided into two groups，with 49 cases in each group. The control group received repeated transcranial magnetic stimulation and continued to take it for 8 weeks. The observation group was given Guizhi Longgu Muli Decoction combined with repeated transcranial magnetic stimulation for 8 weeks. The clinical efficacy and adverse reactions were evaluated. The levels of interleukin-1β（IL-1β），interleukin-6（IL-6），C-reactive protein（CRP），self rating anxiety scale（SAS），self rating depression scale（SDS）before and after 8 weeks of treatment were compared.
Results The clinical efficacy of the control group was lower than that of the observation group，and the difference was statistically significant（P<0.05）. The levels of serum IL-1β，IL-6 and CRP in the control group after 8 weeks of treatment in the observation group［（32.81±5.80）ng/mL，（20.15±3.56）ng/mL，（8.46±2.15）mg/L］were higher than those in the observation group［（28.63±5.47）ng/mL，（14.08±3.12）ng/mL，（5.13±1.86）mg/L］，with statistical significance（P<0.05）. After 8 weeks of treatment，the SAS score［（49.81±1.63）points］and SDSscore［（52.10±1.22）points］in the control group were higher than those in the observation group［（48.42±1.56）points］and［（50.06±1.16）points］，with statistical significance（P<0.05）. There was no statistically significant difference in total adverse reactions between the two groups（P>0.05）.
Conclusion Guizhi Longgu Muli Decoction combined with repeated transcranial magnetic stimulation can improve the symptoms of anxiety and depression in COPD patients with anxiety and depression，reduce inflammatory reaction，and has high safety.
, authors=Jinquan HE, Mengqin LU, Congcong LIU, Limei LI, authorsList=Jinquan HE, Mengqin LU, Congcong LIU, Limei LI, authorCompany=null, correspAuthors=Limei LI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322926137818624845, articleId=1322926134811308863, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=桂枝龙骨牡蛎汤联合重复经颅磁刺激在慢性阻塞性肺疾病合并焦虑抑郁症中的应用, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 评估桂枝龙骨牡蛎汤联合重复经颅磁刺激在慢性阻塞性肺疾病（Chronic obstructive pulmonary disease，COPD）合并焦虑抑郁症中的应用。
方法 采用前瞻性研究方式，选取COPD合并焦虑抑郁症患者98例。按照随机数字表分组，每组49例。对照组予以重复经颅磁刺激，持续8周；观察组予以桂枝龙骨牡蛎汤联合重复经颅磁刺激，持续8周。评价疗效和不良反应，治疗前和治疗8周评定白介素-1β（Interleukin-1β，IL-1β）、白介素-6（Interleukin-6，IL-6）、C反应蛋白（C-reactive protein，CRP）和焦虑自评量表（Self-rating anxiety scale，SAS）、抑郁自评量表（Self-rating depression scale，SDS），相互比较。
结果 对照组的临床疗效低于观察组，差异有统计学意义（P<0.05）。治疗8周对照组血清IL-1β［（32.81±5.80）ng/mL］、IL-6［（20.15±3.56）ng/mL］、CRP［（8.46±2.15）mg/mL］高于观察组［（28.63±5.47）ng/mL、（14.08±3.12）ng/mL、（5.13±1.86）ng/L］，差异有统计学意义（P<0.05）。治疗8周对照组SAS评分［（49.81±1.63）分］、SDS评分［（52.10±1.22）分］高于观察组［（48.42±1.56）分、（50.06±1.16）分］，差异有统计学意义（P<0.05）。两组总不良反应比较，差异无统计学意义（P>0.05）。
结论 桂枝龙骨牡蛎汤联合重复经颅磁刺激应用于COPD合并焦虑抑郁症，可以改善焦虑、抑郁症状，减轻炎症反应，并且安全性高。
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何金泉（1983-），男，湖南郴州人，副主任医师，学士，研究方向：精神病学。
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Thorac Soc, refType=null, unstructuredReference=BENZO R，HOULT J，MCEVOY C，
et al. Promoting chronic obstructive pulmonary disease wellness through remote monitoring and health coaching：a clinical trial［J］.
Ann Am Thorac Soc，
2022，
19（11）：1808-1817., articleTitle=Promoting chronic obstructive pulmonary disease wellness through remote monitoring and health coaching：a clinical trial, refAbstract=null), Reference(id=1322926142457525115, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2022, volume=71, issue=284, pageStart=46, pageEnd=48, url=null, language=null, rfNumber=［2］, rfOrder=1, authorNames=MAZET-CARPENTIER A, MAOZ Z, SUDRESJL, journalName=La Rev De L’infirmière, refType=null, unstructuredReference=MAZET-CARPENTIER A，MAOZ Z，SUDRESJL，
et al. Bronchopneumopathie chronique obstructive：dimensions somato-psychologiques［J］.
La Rev De L’infirmière，
2022，
71（284）：46-48., articleTitle=Bronchopneumopathie chronique obstructive：dimensions somato-psychologiques, refAbstract=null), Reference(id=1322926142562382716, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2021, volume=34, issue=2, pageStart=109, pageEnd=112, url=null, language=null, rfNumber=［3］, rfOrder=2, authorNames=潘惠, 杨忠, 张小弟, journalName=精神医学杂志, refType=null, unstructuredReference=潘惠，杨忠，张小弟，
等. 不同刺激参数重复经颅磁刺激对抑郁症残留失眠症状的随机对照研究［J］.
精神医学杂志，
2021，
34（2）：109-112., articleTitle=不同刺激参数重复经颅磁刺激对抑郁症残留失眠症状的随机对照研究, refAbstract=null), Reference(id=1322926142637880189, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2015, volume=11, issue=21, pageStart=63, pageEnd=64, url=null, language=null, rfNumber=［4］, rfOrder=3, authorNames=李茗, 崔玉琴, 王飞, journalName=亚太传统医药, refType=null, unstructuredReference=李茗，崔玉琴，王飞. 试论慢性阻塞性肺疾病合并抑郁症的中医病机与治疗［J］.
亚太传统医药，
2015，
11（21）：63-64., articleTitle=试论慢性阻塞性肺疾病合并抑郁症的中医病机与治疗, refAbstract=null), Reference(id=1322926142700794750, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2022, volume=42, issue=6, pageStart=1414, pageEnd=1420, url=null, language=null, rfNumber=［5］, rfOrder=4, authorNames=赵忠伟, 李妍, 王纪伟, journalName=中国老年学杂志, refType=null, unstructuredReference=赵忠伟，李妍，王纪伟，
等. 基于“异病同治”理论桂枝加龙骨牡蛎汤治疗老年人不寐的作用机制［J］.
中国老年学杂志，
2022，
42（6）：1414-1420., articleTitle=基于“异病同治”理论桂枝加龙骨牡蛎汤治疗老年人不寐的作用机制, refAbstract=null), Reference(id=1322926142776292223, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2021, volume=44, issue=3, pageStart=170, pageEnd=205, url=null, language=null, rfNumber=［6］, rfOrder=5, authorNames=中华医学会呼吸病学分会慢性阻塞性肺疾病学组, 中国医师协会呼吸医师分会慢性阻塞性肺疾病工作委员会, journalName=中华结核和呼吸杂志, refType=null, unstructuredReference=中华医学会呼吸病学分会慢性阻塞性肺疾病学组，中国医师协会呼吸医师分会慢性阻塞性肺疾病工作委员会. 慢性阻塞性肺疾病诊治指南（2021年修订版）［J］.
中华结核和呼吸杂志，
2021，
44（3）：170-205., articleTitle=慢性阻塞性肺疾病诊治指南（2021年修订版）, refAbstract=null), Reference(id=1322926142860178304, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2002, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［7］, rfOrder=6, authorNames=郑筱萸, journalName=中药新药临床研究指导原则, refType=null, unstructuredReference=郑筱萸.
中药新药临床研究指导原则［M］. 北京：中国医药科技出版社，
2002., articleTitle=null, refAbstract=null), Reference(id=1322926142973424514, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=1994, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［8］, rfOrder=7, authorNames=国家中医药管理局, journalName=null, refType=null, unstructuredReference=国家中医药管理局. 中医病证诊断疗效标准：ZY/T001. 1-001. 9-94［S］. 南京：南京大学出版社，
1994., articleTitle=null, refAbstract=null), Reference(id=1322926143074087811, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2018, volume=7, issue=1, pageStart=4, pageEnd=9, url=null, language=null, rfNumber=［9］, rfOrder=8, authorNames=中国医师协会神经调控专业委员会电休克与神经刺激学组, journalName=转化医学杂志, refType=null, unstructuredReference=中国医师协会神经调控专业委员会电休克与神经刺激学组. 重复经颅磁刺激治疗专家共识［J］.
转化医学杂志，
2018，
7（1）：4-9., articleTitle=重复经颅磁刺激治疗专家共识, refAbstract=null), Reference(id=1322926143162168196, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2019, volume=103, issue=3, pageStart=577, pageEnd=584, url=null, language=null, rfNumber=［10］, rfOrder=9, authorNames=CORNELISON S D, PASCUAL R M, journalName=Med Clin North Am, refType=null, unstructuredReference=CORNELISON S D，PASCUAL R M. Pulmonary rehabilitation in the management of chronic lung disease［J］.
Med Clin North Am，
2019，
103（3）：577-584., articleTitle=Pulmonary rehabilitation in the management of chronic lung disease, refAbstract=null), Reference(id=1322926143229277061, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2023, volume=207, issue=9, pageStart=1134, pageEnd=1144, url=null, language=null, rfNumber=［11］, rfOrder=10, authorNames=CELLI B R, FABBRI L M, AARON SD, journalName=Am J Respir Crit Care Med, refType=null, unstructuredReference=CELLI B R，FABBRI L M，AARON SD，
et al. Differential diagnosis of suspected chronic obstructive pulmonary disease exacerbations in the acute care setting：best practice［J］.
Am J Respir Crit Care Med，
2023，
207（9）：1134-1144., articleTitle=Differential diagnosis of suspected chronic obstructive pulmonary disease exacerbations in the acute care setting：best practice, refAbstract=null), Reference(id=1322926143355106182, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2019, volume=14, issue=1, pageStart=45, pageEnd=46，50, url=null, language=null, rfNumber=［12］, rfOrder=11, authorNames=祝峰, 但堂群, 曹文滔, journalName=神经损伤与功能重建, refType=null, unstructuredReference=祝峰，但堂群，曹文滔. 重复经颅磁刺激对抑郁症患者的疗效观察［J］.
神经损伤与功能重建，
2019，
14（1）：45-46，50., articleTitle=重复经颅磁刺激对抑郁症患者的疗效观察, refAbstract=null), Reference(id=1322926143443186567, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2017, volume=24, issue=32, pageStart=139, pageEnd=141, url=null, language=null, rfNumber=［13］, rfOrder=12, authorNames=李萍, journalName=中国当代医药, refType=null, unstructuredReference=李萍. 中西医联合治疗慢性阻塞性肺疾病肺脾气虚证合并抑郁症的临床研究［J］.
中国当代医药，
2017，
24（32）：139-141., articleTitle=中西医联合治疗慢性阻塞性肺疾病肺脾气虚证合并抑郁症的临床研究, refAbstract=null), Reference(id=1322926143527072648, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2020, volume=42, issue=9, pageStart=1299, pageEnd=1304, url=null, language=null, rfNumber=［14］, rfOrder=13, authorNames=王勇, 张传红, 滕玲, journalName=河北中医, refType=null, unstructuredReference=王勇，张传红，滕玲. 利肺化痰解忧汤治疗慢性阻塞性肺疾病合并焦虑抑郁的临床研究［J］.
河北中医，
2020，
42（9）：1299-1304., articleTitle=利肺化痰解忧汤治疗慢性阻塞性肺疾病合并焦虑抑郁的临床研究, refAbstract=null), Reference(id=1322926143627735945, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2019, volume=4, issue=35, pageStart=138, pageEnd=139, url=null, language=null, rfNumber=［15］, rfOrder=14, authorNames=张军城, 王旭红, 高洁, journalName=临床医学研究与实践, refType=null, unstructuredReference=张军城，王旭红，高洁，
等. 从“因病致郁”论慢性阻塞性肺疾病合并焦虑抑郁［J］.
临床医学研究与实践，
2019，
4（35）：138-139., articleTitle=从“因病致郁”论慢性阻塞性肺疾病合并焦虑抑郁, refAbstract=null), Reference(id=1322926143707427722, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2022, volume=34, issue=12, pageStart=2230, pageEnd=2233, url=null, language=null, rfNumber=［16］, rfOrder=15, authorNames=王丽萍, 曲妮妮, journalName=中医药临床杂志, refType=null, unstructuredReference=王丽萍，曲妮妮. 基于“少阳主枢”理论探讨COPD合并焦虑抑郁的中医病机［J］.
中医药临床杂志，
2022，
34（12）：2230-2233., articleTitle=基于“少阳主枢”理论探讨COPD合并焦虑抑郁的中医病机, refAbstract=null), Reference(id=1322926143778730891, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2020, volume=42, issue=1, pageStart=94, pageEnd=96, url=null, language=null, rfNumber=［17］, rfOrder=16, authorNames=吕志超, 刘晓静, 郭欢, journalName=国际中医中药杂志, refType=null, unstructuredReference=吕志超，刘晓静，郭欢，
等. 中医药治疗慢性阻塞性肺疾病合并焦虑抑郁研究进展［J］.
国际中医中药杂志，
2020，
42（1）：94-96., articleTitle=中医药治疗慢性阻塞性肺疾病合并焦虑抑郁研究进展, refAbstract=null), Reference(id=1322926143845839756, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2022, volume=40, issue=11, pageStart=137, pageEnd=141, url=null, language=null, rfNumber=［18］, rfOrder=17, authorNames=丁娜娜, 许二平, 张楠, journalName=中华中医药学刊, refType=null, unstructuredReference=丁娜娜，许二平，张楠，
等. 桂枝汤及其类方加减治疗抑郁症的研究新进展［J］.
中华中医药学刊，
2022，
40（11）：137-141., articleTitle=桂枝汤及其类方加减治疗抑郁症的研究新进展, refAbstract=null), Reference(id=1322926143921337229, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2022, volume=63, issue=19, pageStart=1865, pageEnd=1871, url=null, language=null, rfNumber=［19］, rfOrder=18, authorNames=闫德祺, 张星平, 张文慧, journalName=中医杂志, refType=null, unstructuredReference=闫德祺，张星平，张文慧，
等. 桂枝加龙骨牡蛎汤对肺不藏魄型不寐模型大鼠睡眠情况、血清及脑组织5羟色胺水平的影响［J］.
中医杂志，
2022，
63（19）：1865-1871., articleTitle=桂枝加龙骨牡蛎汤对肺不藏魄型不寐模型大鼠睡眠情况、血清及脑组织5羟色胺水平的影响, refAbstract=null), Reference(id=1322926144001029006, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2014, volume=30, issue=4, pageStart=76, pageEnd=79, url=null, language=null, rfNumber=［20］, rfOrder=19, authorNames=郑芳昊, 罗佳波, journalName=中药药理与临床, refType=null, unstructuredReference=郑芳昊，罗佳波. 桂枝对大鼠中枢神经系统作用的研究［J］.
中药药理与临床，
2014，
30（4）：76-79., articleTitle=桂枝对大鼠中枢神经系统作用的研究, refAbstract=null), Reference(id=1322926144076526479, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2019, volume=21, issue=5, pageStart=912, pageEnd=917, url=null, language=null, rfNumber=［21］, rfOrder=20, authorNames=夏小雯, 孙亚, 宋春红, journalName=世界科学技术-中医药现代化, refType=null, unstructuredReference=夏小雯，孙亚，宋春红，
等. 芍药苷抗抑郁的相关研究进展［J］.
世界科学技术-中医药现代化，
2019，
21（5）：912-917., articleTitle=芍药苷抗抑郁的相关研究进展, refAbstract=null), Reference(id=1322926144152023952, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2012, volume=47, issue=12, pageStart=1612, pageEnd=1617, url=null, language=null, rfNumber=［22］, rfOrder=21, authorNames=樊紫周, 赵伟鸿, 果嘉, journalName=药学学报, refType=null, unstructuredReference=樊紫周，赵伟鸿，果嘉，
等. 甘草黄酮的抗抑郁作用及对海马脑区神经再生的保护作用［J］.
药学学报，
2012，
47（12）：1612-1617., articleTitle=甘草黄酮的抗抑郁作用及对海马脑区神经再生的保护作用, refAbstract=null), Reference(id=1322926144244298641, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2021, volume=23, issue=6, pageStart=647, pageEnd=650, url=null, language=null, rfNumber=［23］, rfOrder=22, authorNames=王秀云, 李云, 朱含笑, journalName=中华老年心脑血管病杂志, refType=null, unstructuredReference=王秀云，李云，朱含笑，
等. 甘草苷对脑卒中后抑郁大鼠额前皮质脑源性神经营养因子及Bax和Bcl-2蛋白表达的影响［J］.
中华老年心脑血管病杂志，
2021，
23（6）：647-650., articleTitle=甘草苷对脑卒中后抑郁大鼠额前皮质脑源性神经营养因子及Bax和Bcl-2蛋白表达的影响, refAbstract=null), Reference(id=1322926144319796114, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2018, volume=13, issue=4, pageStart=803, pageEnd=807, url=null, language=null, rfNumber=［24］, rfOrder=23, authorNames=杨淑, 李玲玲, 温瀑, journalName=世界中医药, refType=null, unstructuredReference=杨淑，李玲玲，温瀑，
等. 生姜对COPD寒饮蕴肺证大鼠的干预作用研究［J］.
世界中医药，
2018，
13（4）：803-807., articleTitle=生姜对COPD寒饮蕴肺证大鼠的干预作用研究, refAbstract=null), Reference(id=1322926144399487891, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2022, volume=28, issue=8, pageStart=21, pageEnd=29, url=null, language=null, rfNumber=［25］, rfOrder=24, authorNames=刘蔚, 曹俊岭, 荆志伟, journalName=中国实验方剂学杂志, refType=null, unstructuredReference=刘蔚，曹俊岭，荆志伟，
等. 柴胡加龙骨牡蛎汤对帕金森病伴发抑郁模型大鼠的神经保护作用及对AMPK/mTOR信号通路的影响［J］.
中国实验方剂学杂志，
2022，
28（8）：21-29., articleTitle=柴胡加龙骨牡蛎汤对帕金森病伴发抑郁模型大鼠的神经保护作用及对AMPK/mTOR信号通路的影响, refAbstract=null), Reference(id=1322926146085598100, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2018, volume=null, issue=6, pageStart=357, pageEnd=363, url=null, language=null, rfNumber=［26］, rfOrder=25, authorNames=王秀峰, 曾雪爱, 张瑜, journalName=中医学, refType=null, unstructuredReference=王秀峰，曾雪爱，张瑜，
等. 养心安神药和重镇安神药对失眠大鼠神经递质的影响［J］.
中医学，
2018（6）：357-363., articleTitle=养心安神药和重镇安神药对失眠大鼠神经递质的影响, refAbstract=null), Reference(id=1322926146152706965, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2017, volume=37, issue=12, pageStart=926, pageEnd=932, url=null, language=null, rfNumber=［27］, rfOrder=26, authorNames=窦静波, 庞红燕, 李云芳, journalName=国际呼吸杂志, refType=null, unstructuredReference=窦静波，庞红燕，李云芳，
等. COPD合并焦虑、抑郁的血清生物标志物研究［J］.
国际呼吸杂志，
2017，
37（12）：926-932., articleTitle=COPD合并焦虑、抑郁的血清生物标志物研究, refAbstract=null), Reference(id=1322926146224010134, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2016, volume=37, issue=4, pageStart=629, pageEnd=631, url=null, language=null, rfNumber=［28］, rfOrder=27, authorNames=龙莉, 熊彬, journalName=广东医学, refType=null, unstructuredReference=龙莉，熊彬. 慢性阻塞性肺疾病合并抑郁症与炎症因子的相关性［J］.
广东医学，
2016，
37（4）：629-631., articleTitle=慢性阻塞性肺疾病合并抑郁症与炎症因子的相关性, refAbstract=null), Reference(id=1322926146307896215, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2018, volume=32, issue=10, pageStart=90, pageEnd=91, url=null, language=null, rfNumber=［29］, rfOrder=28, authorNames=闫景霞, 徐晶, 李维浩, journalName=中国初级卫生保健, refType=null, unstructuredReference=闫景霞，徐晶，李维浩，
等. 慢性阻塞性肺疾病患者血清细胞因子与抑郁情绪的相关分析［J］.
中国初级卫生保健，
2018，
32（10）：90-91., articleTitle=慢性阻塞性肺疾病患者血清细胞因子与抑郁情绪的相关分析, refAbstract=null), Reference(id=1322926146387587992, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, doi=null, pmid=null, pmcid=null, year=2019, volume=16, issue=11, pageStart=1567, pageEnd=1569, url=null, language=null, rfNumber=［30］, rfOrder=29, authorNames=尹小华, 甘学琴, journalName=检验医学与临床, refType=null, unstructuredReference=尹小华，甘学琴. COPD患者WBC、CRP、PCT水平变化及其临床意义［J］.
检验医学与临床，
2019，
16（11）：1567-1569., articleTitle=COPD患者WBC、CRP、PCT水平变化及其临床意义, refAbstract=null)], funds=[Fund(id=1322926142268781433, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, awardId=21C0711, language=CN, fundingSource=湖南省教育厅一般项目(21C0711), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1322926138024145742, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, xref=null, ext=[AuthorCompanyExt(id=1322926138032534351, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, companyId=1322926138024145742, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chenzhou First People's Hospital，Chenzhou 423000，Hunan，China), AuthorCompanyExt(id=1322926138040922960, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, companyId=1322926138024145742, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=郴州市第一人民医院，湖南 郴州 423000)])], figs=[ArticleFig(id=1322926139806724974, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 性别/［例（%）］ | 平均年龄/（岁， ±s） | 平均病程/（年， ±s） | 平均SAS评分/（分， ±s） | 平均SDS评分/（分， ±s） |
|---|
| 男 | 女 |
|---|
| 对照组 | 49 | 29（59.18） | 20（40.82） | 59.82±6.35 | 12.41±3.81 | 54.61±2.12 | 57.26±1.51 |
| 观察组 | 49 | 25（51.02） | 24（48.98） | 60.43±6.08 | 12.67±3.42 | 55.10±2.01 | 57.58±1.82 |
| t/χ2 | | 0.660 | 0.486 | 0.355 | 1.174 | 0.947 |
| P值 | | 0.417 | 0.628 | 0.723 | 0.243 | 0.346 |
), ArticleFig(id=1322926139878028144, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=CN, label=表1, caption=
两组慢性阻塞性肺疾病合并焦虑抑郁症患者各项数据分析
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| 组别 | 例数 | 性别/［例（%）］ | 平均年龄/（岁，±s） | 平均病程/（年，±s） | 平均SAS评分/（分，±s） | 平均SDS评分/（分，±s） |
|---|
| 男 | 女 |
|---|
| 对照组 | 49 | 29（59.18） | 20（40.82） | 59.82±6.35 | 12.41±3.81 | 54.61±2.12 | 57.26±1.51 |
| 观察组 | 49 | 25（51.02） | 24（48.98） | 60.43±6.08 | 12.67±3.42 | 55.10±2.01 | 57.58±1.82 |
| t/χ2 | | 0.660 | 0.486 | 0.355 | 1.174 | 0.947 |
| P值 | | 0.417 | 0.628 | 0.723 | 0.243 | 0.346 |
), ArticleFig(id=1322926139945137009, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 基本治愈 | 显效 | 有效 | 无效 | 总有效 |
|---|
| 对照组 | 49 | 11（22.45） | 15（30.61） | 15（30.61） | 8（16.33） | 41（83.67） |
| 观察组 | 49 | 16（32.65） | 18（36.73） | 13（26.53） | 2（4.08） | 47（95.92） |
| χ2值 | | | | | | 4.009 |
| P值 | | | | | | 0.045 |
), ArticleFig(id=1322926141589304178, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=CN, label=表2, caption=
两组慢性阻塞性肺疾病合并焦虑抑郁症患者临床疗效比较
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 基本治愈 | 显效 | 有效 | 无效 | 总有效 |
|---|
| 对照组 | 49 | 11（22.45） | 15（30.61） | 15（30.61） | 8（16.33） | 41（83.67） |
| 观察组 | 49 | 16（32.65） | 18（36.73） | 13（26.53） | 2（4.08） | 47（95.92） |
| χ2值 | | | | | | 4.009 |
| P值 | | | | | | 0.045 |
), ArticleFig(id=1322926141673190259, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | IL-1β/（ng/mL） | IL-6/（ng/mL） | CRP/（mg/L） |
|---|
| 治疗前 | 治疗8周 | 治疗前 | 治疗8周 | 治疗前 | 治疗8周 |
|---|
| 对照组 | 49 | 71.25±8.96 | 32.81±5.80# | 29.45±5.73 | 20.15±3.56# | 14.52±3.70 | 8.46±2.15# |
| 观察组 | 49 | 70.43±9.27 | 28.63±5.47# | 30.12±5.80 | 14.08±3.12# | 15.03±3.81 | 5.13±1.86# |
| t值 | | 0.445 | 3.670 | 0.575 | 8.976 | 0.672 | 8.199 |
| P值 | | 0.657 | 0.000 | 0.566 | 0.000 | 0.503 | 0.000 |
), ArticleFig(id=1322926141803213684, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=CN, label=表3, caption=
两组慢性阻塞性肺疾病合并焦虑抑郁症患者治疗前后炎症因子指标比较（
±s）
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | IL-1β/（ng/mL） | IL-6/（ng/mL） | CRP/（mg/L） |
|---|
| 治疗前 | 治疗8周 | 治疗前 | 治疗8周 | 治疗前 | 治疗8周 |
|---|
| 对照组 | 49 | 71.25±8.96 | 32.81±5.80# | 29.45±5.73 | 20.15±3.56# | 14.52±3.70 | 8.46±2.15# |
| 观察组 | 49 | 70.43±9.27 | 28.63±5.47# | 30.12±5.80 | 14.08±3.12# | 15.03±3.81 | 5.13±1.86# |
| t值 | | 0.445 | 3.670 | 0.575 | 8.976 | 0.672 | 8.199 |
| P值 | | 0.657 | 0.000 | 0.566 | 0.000 | 0.503 | 0.000 |
), ArticleFig(id=1322926141874516853, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | SAS评分 | SDS评分 |
|---|
| 治疗前 | 治疗8周 | 治疗前 | 治疗8周 |
|---|
| 对照组 | 49 | 54.61±2.12 | 49.81±1.63# | 57.26±1.51 | 52.10±1.22# |
| 观察组 | 49 | 55.10±2.01 | 48.42±1.56# | 57.58±1.82 | 50.06±1.16# |
| t值 | | 1.174 | 4.313 | 0.947 | 8.483 |
| P值 | | 0.243 | 0.000 | 0.346 | 0.000 |
), ArticleFig(id=1322926141970985846, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=CN, label=表4, caption=
两组慢性阻塞性肺疾病合并焦虑抑郁症患者治疗前后焦虑抑郁状态比较（
±s）
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | SAS评分 | SDS评分 |
|---|
| 治疗前 | 治疗8周 | 治疗前 | 治疗8周 |
|---|
| 对照组 | 49 | 54.61±2.12 | 49.81±1.63# | 57.26±1.51 | 52.10±1.22# |
| 观察组 | 49 | 55.10±2.01 | 48.42±1.56# | 57.58±1.82 | 50.06±1.16# |
| t值 | | 1.174 | 4.313 | 0.947 | 8.483 |
| P值 | | 0.243 | 0.000 | 0.346 | 0.000 |
), ArticleFig(id=1322926142046483319, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 恶心呕吐 | 头晕 | 发热 | 皮疹 | 肝酶异常 | 总不良反应 |
|---|
| 对照组 | 49 | 3（6.12） | 4（8.16） | 2（4.08） | 1（2.04） | 0（0.00） | 10（20.41） |
| 观察组 | 49 | 2（4.08） | 5（10.20） | 0（0.00） | 3（6.12） | 1（2.04） | 11（22.45） |
| χ2值 | | | | | | | 0.061 |
| P值 | | | | | | | 0.806 |
), ArticleFig(id=1322926142121980792, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322926134811308863, language=CN, label=表5, caption=
两组慢性阻塞性肺疾病合并焦虑抑郁症患者不良反应
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 恶心呕吐 | 头晕 | 发热 | 皮疹 | 肝酶异常 | 总不良反应 |
|---|
| 对照组 | 49 | 3（6.12） | 4（8.16） | 2（4.08） | 1（2.04） | 0（0.00） | 10（20.41） |
| 观察组 | 49 | 2（4.08） | 5（10.20） | 0（0.00） | 3（6.12） | 1（2.04） | 11（22.45） |
| χ2值 | | | | | | | 0.061 |
| P值 | | | | | | | 0.806 |
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