Article(id=1322923537169784878, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2025.05.007, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793339149992, onlineDateStr=2026-10-30, pubDate=1746806400000, pubDateStr=2025-05-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793339149992, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793339149992, creator=13701087609, updateTime=1793339149992, updator=13701087609, issue=Issue{id=1322923490592043032, tenantId=1146029695717560320, journalId=1255847919539208197, year='2025', volume='43', issue='5', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1746806400000', pubDateStr='2025-05-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793339138887, creator='13701087609', updateTime=1793340572227, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322929502539612595, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322929502539612596, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=32, endPage=34, ext={EN=ArticleExt(id=1322923537354334255, articleId=1322923537169784878, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Characteristics of Carbapenem Resistant Klebsiella Pneumoniae Sepsis in Children and Research Progress on Traditional Chinese Medicine Treatment, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

In recentyears，with thewide application of antibacterial drugs，their drug resistance is rising，and the development of drug resistance is far greater than the development of antibacterial drugs，leading to a serious threat to human life and health and increasing the economic burden ofmedical and health care. The detection rate of carbapenem resistant Klebsiella pneumoniae（CRKP）in pediatric wards in China is increasing. CRPK sepsis in children lacks specific clinicalmanifestations，and its onset is hidden. But it has strong pathogenicity and rapid progression，and is prone tomultiple organ failure. Carbapenem antibiotics are still themainmeans to treat CRKP infection. With the in-depth study of CRKP sepsis in traditional Chinesemedicine，more and more attention has been paid to the treatment of CRKP sepsis with traditional Chinesemedicine. This article aimed to review the characteristics of carbapenem resistant Klebsiella pneumoniae sepsis in children and the research progress of traditional Chinese medicine treatment.

, authors=Yan WANG, Jingjing LING, Danli ZHOU, Huanqing GE, authorsList=Yan WANG, Jingjing LING, Danli ZHOU, Huanqing GE, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322923537920565298, articleId=1322923537169784878, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=儿童耐碳青霉烯类肺炎克雷伯杆菌脓毒症特点以及中医治疗的研究进展, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

随着近年来抗菌药物的广泛应用，其耐药性不断上升，耐药发展远大于抗菌药物的研发，严重威胁人类生命，加重医疗卫生经济负担。我国儿科病房对耐碳青霉烯类肺炎克雷伯杆菌（Carbapenem resistant Klebsiella pneumoniae，CRKP）检出率不断增长。儿童CRPK脓毒症缺乏特异临床表现，起病隐匿，但致病性强、进展迅速，容易出现多器官衰竭等。碳青霉烯类抗菌药物仍为治疗CRKP感染的主要手段。随着中医对CRKP脓毒症的深入研究，中医药用于CRKP脓毒症方面的治疗越来越受到重视。对儿童耐碳青霉烯类肺炎克雷伯杆菌脓毒症特点以及中医治疗的研究进展作一综述。

, authors=王燕, 凌菁菁, 周丹丽, 葛焕青, authorsList=王燕, 凌菁菁, 周丹丽, 葛焕青, authorCompany=null, correspAuthors=null, authorNote=, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=i4VDgfu+V6bC4qLrrbUX3A==, magXml=HAbkpkhjwDVWx8X6FNGunA==, pdfUrl=null, pdf=4rkHw+YDxbQek1X75PPbdw==, pdfFileSize=1614704, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=vCqgvO0vCa/TuWv2TfpdEw==, mapNumber=null, fund=null)}, authors=[Author(id=1322923538201583671, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923537169784878, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923538298052665, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923537169784878, authorId=1322923538201583671, language=EN, stringName=Yan WANG, firstName=Yan, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Wuxi Children＇s Hospital，Wuxi 214000，Jiangsu，China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923538356772922, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923537169784878, authorId=1322923538201583671, language=CN, stringName=王燕, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=无锡市儿童医院，江苏 无锡 214000, bio={"content":"

王燕（1978-），女，江苏连云港人，主任药师，硕士，研究方向：药事管理、临床药学（儿科）。

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王燕（1978-），女，江苏连云港人，主任药师，硕士，研究方向：药事管理、临床药学（儿科）。

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