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Research Progress of Mechanism of Tumor Multidrug Resistance and Reversal by Traditional Chinese Medicine
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Yanjuan LIU1, 2, Yuhong CAO2, 3, *, Rong KUANG1, 2, *
Chinese Pharmaceutical Journal | 2024, 59(7) : 561 - 570
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Chinese Pharmaceutical Journal | 2024, 59(7): 561-570
Research Progress of Mechanism of Tumor Multidrug Resistance and Reversal by Traditional Chinese Medicine
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Yanjuan LIU1, 2, Yuhong CAO2, 3, *, Rong KUANG1, 2, *
Affiliations
  • 1 Collaboration Innovation Center of Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310032, China
  • 2 NMPA Key Laboratory for Animal Alternative Testing Technology of Cosmetics, Zhejiang Institute for Food and Drug Control, Hangzhou 310052, China
  • 3 Institute of Translational Medicine, Zhejiang University, Hangzhou 310029, China
Published: 2024-04-08 doi: 10.11669/cpj.2024.07.001
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Chemotherapy is one of the commonly used methods for tumor treatment, but the occurrence of multidrug resistance (MDR) in tumors has added great difficulties for tumor treatment, causing serious harm to patients' physiology and psychology. At present, there is a relative lack of research and treatment on tumor resistance in clinical practice, and finding reversal agents and strategies for tumor resistance is an urgent problem to be solved. This article reviews the mechanism of tumor multidrug resistance and its reversal methods and research status of Chinese medicine as reverse agent, aiming to provide reference for future research.

multidrug resistance  /  transporter protein  /  P-glycoprotein  /  Chinese medicine reversal
Yanjuan LIU, Yuhong CAO, Rong KUANG. Research Progress of Mechanism of Tumor Multidrug Resistance and Reversal by Traditional Chinese Medicine[J]. Chinese Pharmaceutical Journal, 2024 , 59 (7) : 561 -570 . DOI: 10.11669/cpj.2024.07.001
Year 2024 volume 59 Issue 7
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Article Info
doi: 10.11669/cpj.2024.07.001
  • Receive Date:2023-08-28
  • Online Date:2026-04-08
  • Published:2024-04-08
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  • Received:2023-08-28
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Affiliations
    1 Collaboration Innovation Center of Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310032, China
    2 NMPA Key Laboratory for Animal Alternative Testing Technology of Cosmetics, Zhejiang Institute for Food and Drug Control, Hangzhou 310052, China
    3 Institute of Translational Medicine, Zhejiang University, Hangzhou 310029, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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