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Evaluation of Effects of Different Drying Methods on Multiple Index Constituents in Lysimachiae Herba Based on Multivariate Statistical Analysis
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Yongyi ZHOU1, Haijie CHEN1, Jia XUE1, Lisi ZOU1, *, Nan WU1, Jiahuan YUAN1, Xunhong LIU1, 2, *, Zhichen CAI1, Cuihua CHEN1, Wei YANG1, Jianming CHENG1, 2
Chinese Pharmaceutical Journal | 2024, 59(5) : 398 - 408
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Chinese Pharmaceutical Journal | 2024, 59(5): 398-408
Evaluation of Effects of Different Drying Methods on Multiple Index Constituents in Lysimachiae Herba Based on Multivariate Statistical Analysis
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Yongyi ZHOU1, Haijie CHEN1, Jia XUE1, Lisi ZOU1, *, Nan WU1, Jiahuan YUAN1, Xunhong LIU1, 2, *, Zhichen CAI1, Cuihua CHEN1, Wei YANG1, Jianming CHENG1, 2
Affiliations
  • 1 School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China
  • 2 Jiangsu Province Engineering Research Center of Classical Prescription, Nanjing 210023, China
Published: 2024-03-08
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OBJECTIVE To explore the effects of different drying methods on multiple index constituents in Lysimachiae Herba. METHODS A comprehensive analytical method employed with ultra high performance liquid chromatography with triple quadrupole linear ion trap mass spectrometry (UHPLC-QTRAP-MS/MS) was used for simultaneous determination of forty-four constituents including flavonoids, organic acids, amino acids, and nucleosides in Lysimachiae Herba. The hierarchical cluster analysis (HCA), gray relation analysis (GRA), and technique for order preference by similarity to ideal solution(TOPSIS) methods were applied to comprehensively analyze and evaluate the results of multiple index constituents. RESULTS HCA results showed that seven different drying methods were mainly divided into two categories, the first category was sun drying and shady drying, and the second category was drying at different temperatures, microwave drying, and freeze drying. In addition, GRA and TOPSIS results showed that sun drying samples had better quality, and shady drying and freeze drying could be used as alternative drying methods. CONCLUSION This study can provide a basis for revealing the scientific connotation of traditional drying method of Lysimachiae Herba, and provide information for the optimization of drying method during the processing of Lysimachiae Herba.

Lysimachiae Herba  /  drying method  /  UHPLC-QTRAP-MS/MS  /  multiple index constituent  /  multivariate statistical analysis
Yongyi ZHOU, Haijie CHEN, Jia XUE, Lisi ZOU, Nan WU, Jiahuan YUAN, Xunhong LIU, Zhichen CAI, Cuihua CHEN, Wei YANG, Jianming CHENG. Evaluation of Effects of Different Drying Methods on Multiple Index Constituents in Lysimachiae Herba Based on Multivariate Statistical Analysis[J]. Chinese Pharmaceutical Journal, 2024 , 59 (5) : 398 -408 .
Year 2024 volume 59 Issue 5
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  • Receive Date:2023-01-04
  • Online Date:2026-04-08
  • Published:2024-03-08
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  • Received:2023-01-04
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    1 School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China
    2 Jiangsu Province Engineering Research Center of Classical Prescription, Nanjing 210023, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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