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New Progress on Preperation, Structural Characterization and Pharmacological Activities of Sea buckthorn Polysaccharides
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Na LING1, 2, Haiyan TIAN1, 2, Mingze GAO1, 2, Qiyao WANG3, Guiguo XU1, 2, Chenfeng JI1, 2, *
Chinese Pharmaceutical Journal | 2024, 59(9) : 757 - 767
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Chinese Pharmaceutical Journal | 2024, 59(9): 757-767
New Progress on Preperation, Structural Characterization and Pharmacological Activities of Sea buckthorn Polysaccharides
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Na LING1, 2, Haiyan TIAN1, 2, Mingze GAO1, 2, Qiyao WANG3, Guiguo XU1, 2, Chenfeng JI1, 2, *
Affiliations
  • 1 Pharmaceutical Engineering Technology Research Center, Harbin University of Commerce, Harbin 150076,China
  • 2 Engineering Research Center for Natural Antitumor Drugs, Ministry of Education P.R. China, Harbin 150076,China
  • 3 School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
Published: 2024-05-08 doi: 10.11669/cpj.2024.09.001
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Hippophae rhamnoides L. is a high-quality medicinal and edible plant with rich nutritional values and a wide range of biological activities. It has been used to improve hyperglycemia, hyperlipidemia, liver injury and prevent cardiovascular diseases. Sea buckthorn polysaccharides (SBPs) are one of the most important bioactive components of Hippophae rhamnoides L.. The preperation methods of SBPs include hot water extraction, ultrasonic-assisted extraction, microwave-assisted extraction, and flash extraction. Different preperation methods lead to different configurations and biological activities of SBPs. Furthermore, these biological activities are related to the chemical structure of SBPs, including the relative molecular weight, monosaccharide composition, glycosidic bond and three-dimensional structure. Modern pharmacological studies have demonstrated that SBPs possess various activities, including hepatoprotective, anti-inflammatory, immunomodulatory, anti-tumor, antioxidant activity, as well as the regulation of blood sugar and lipid metabolism disorder, which will exhibit excellent development value in functional food and medicament. However, few studies on the structure-function relationship of SBPs have been reported. In this paper, the preperation methods, structure characterization, pharmacological activities and the utilization of SBPs were systematically reviewed, the structure-activity relationship and application prospect were discussed, which will provide a theoretical basis for a further research and development and utilization of SBPs.

Hippophae rhamnoides L.  /  polysaccharides preperation  /  structure characterization  /  pharmacological activity  /  hepatoprotection
Na LING, Haiyan TIAN, Mingze GAO, Qiyao WANG, Guiguo XU, Chenfeng JI. New Progress on Preperation, Structural Characterization and Pharmacological Activities of Sea buckthorn Polysaccharides[J]. Chinese Pharmaceutical Journal, 2024 , 59 (9) : 757 -767 . DOI: 10.11669/cpj.2024.09.001
Year 2024 volume 59 Issue 9
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Article Info
doi: 10.11669/cpj.2024.09.001
  • Receive Date:2023-03-31
  • Online Date:2025-11-25
  • Published:2024-05-08
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  • Received:2023-03-31
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Affiliations
    1 Pharmaceutical Engineering Technology Research Center, Harbin University of Commerce, Harbin 150076,China
    2 Engineering Research Center for Natural Antitumor Drugs, Ministry of Education P.R. China, Harbin 150076,China
    3 School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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