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OBJECTIVE To analyze the intervention effect of prescription pre-review and Six Sigma management model on the qualified rate of outpatient prescriptions to improve the quality of pharmaceutical care and ensure the safety, rationality, and effectiveness of medication in patients. METHODS The qualified rates of outpatient prescriptions in Beijing Hospital from April 2020 to March 2024 were collected. The multi-stage model of interrupted time series analysis (ITSA) was used to analyze the changes in the qualified rate of outpatient prescriptions in three stages: before and after the pre-review system was implemented in the whole department, as well as the implementation of Six Sigma management method based on the pre-review. RESULTS The ITSA showed that the qualified rate of outpatient prescriptions in our hospital was stable around 86.56% before the pre-review was carried out in all departments. After the implementation of pre-review, the qualified rate of prescriptions in that month increased by 9.81%. In November 2021, after the implementation of define measure analyze improve control (DMAIC) management based on prescription pre-review, the qualified rate of prescriptions in the month increased to 98.07%, reaching the target value, and the qualified rate of prescriptions continued to increase with a monthly trend of 0.05%. CONCLUSION The implementation of prescription pre-review and Six Sigma management is conducive to the formation of a closed-loop management model of pre-review, in-process intervention, post-comment, result publicity, and timely communication and feedback, which significantly improves the level of rational drug use in the outpatient department, better standardizes the prescribing behavior of doctors, promotes the communication and cooperation between pharmacists and physicians, and ensures the medication safety of drug use for patients.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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