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Chemical Constituents of Ethyl Acetate Extract from Moringa oleifera Leaves
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ZHOU Lipeng, LUO Xiaowei, WANG Shukai, CHANG Zihao, HU Qian, LIU Yuqi, GAO Ye, CHEN Yinxin, WANG Baojin, HUANG Ya, WANG Zhaohui, CUI Yitong, LIU Yue*, ZHANG Lanzhen*
Chinese Pharmaceutical Journal | 2024, 59(2) : 136 - 141
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Chinese Pharmaceutical Journal | 2024, 59(2): 136-141
Chemical Constituents of Ethyl Acetate Extract from Moringa oleifera Leaves
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ZHOU Lipeng, LUO Xiaowei, WANG Shukai, CHANG Zihao, HU Qian, LIU Yuqi, GAO Ye, CHEN Yinxin, WANG Baojin, HUANG Ya, WANG Zhaohui, CUI Yitong, LIU Yue*, ZHANG Lanzhen*
Affiliations
  • School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China
Published: 2024-01-22 doi: 10.11669/cpj.2024.02.005
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OBJECTIVE To study the chemical constituents of ethyl acetate extract from Moringa oleifera leaves. METHODS The chemical constituents of ethyl acetate extract from Moringa oleifera leaves were isolated and purified by chromatographic methods. The structures of isolated compounds were identified by MS and NMR data. DPPH and ABTS were used to test the antioxidant activities of the compounds in vitro. RESULTS Fourteen compounds were isolated from ethyl acetate extract of Moringa oleifera leaves and identified as icariside B1 (1), (3S)-O-β-D-glucopyranosyl-6-[3-oxo-(2S)-butenylideny]-1, 1, 5-trimethylcyclohexan-(5R)-ol (2), icariside B2 (3), 9-hydroxy-megastigma-4, 7-dien-3-one-9-O-β-D-glucopyranoside (4), tectorigenin (5), tectoridin (6), iristectorin A (7), iristectorin B (8), 5-hydroxy-2-hydroxymethylpyridine (9), androsin (10), 3, 4, 5-trimethoxyphenyl-1-O-β-D-glucopyranoside (11), 1-O-(4-hydroxymethylphenyl)-α-L-rhamnopyranoside (12), benzyl-O-β-D-glucopyranoside (13) and methyl 2-[4-(α-L-rhamnopyranosyl) phenyl] acetate (14), respectively. Among them, compounds 6, 7 and 8 had certain antioxidant activities, but the activities were weaker than that of vitamin C as positive control. CONCLUSION Compounds 2-11 are isolated from Moringa genus for the first time.

Moringa oleifera Leaf  /  structure identification  /  isoflavone  /  antioxidant activity
周立鹏, 雒晓卫, 王树楷, 常子豪, 胡倩, 刘宇琦, 高晔, 陈尹心, 王保锦, 黄雅, 王朝慧, 崔艺彤, 刘越, 张兰珍. 辣木叶乙酸乙酯部位化学成分研究. 中国药学杂志, 2024 , 59 (2) : 136 -141 . DOI: 10.11669/cpj.2024.02.005
ZHOU Lipeng, LUO Xiaowei, WANG Shukai, CHANG Zihao, HU Qian, LIU Yuqi, GAO Ye, CHEN Yinxin, WANG Baojin, HUANG Ya, WANG Zhaohui, CUI Yitong, LIU Yue, ZHANG Lanzhen. Chemical Constituents of Ethyl Acetate Extract from Moringa oleifera Leaves[J]. Chinese Pharmaceutical Journal, 2024 , 59 (2) : 136 -141 . DOI: 10.11669/cpj.2024.02.005
Year 2024 volume 59 Issue 2
539
272
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doi: 10.11669/cpj.2024.02.005
  • Receive Date:2023-03-21
  • Online Date:2025-11-13
  • Published:2024-01-22
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  • Received:2023-03-21
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    School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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