Styrene-isoprene-styrene block copolymer pressure sensitive adhesive (SIS-PSA) is an ideal commercial adhesive with unique environmental attributes and high processability. As a key excipient for patches, SIS-PSA has a significant impact on the key properties such as drug release and adhesion. Since the performance of SIS-PSA is determined by a combination of different components, a thorough understanding of these components is essential for patch formulation design. This article discusses the impact of each component in SIS-PSA on the key performance of patches, summarizes the composition and application of marketed SIS-PSA patches, and focuses on patch formulation design oriented towards clinical needs, aiming to provide a reference for the research and development of SIS-PSA patches.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |