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Research Progress on SIS Pressure-Sensitive Adhesive: Functionality and Application in Patch Formulation Design
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Difu SHI1, Zhiyuan HOU1, Xiangcheng ZHAO1, Jinsong DING1, 2, *
Chinese Pharmaceutical Journal | 2025, 60(7) : 673 - 679
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Chinese Pharmaceutical Journal | 2025, 60(7): 673-679
Research Progress on SIS Pressure-Sensitive Adhesive: Functionality and Application in Patch Formulation Design
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Difu SHI1, Zhiyuan HOU1, Xiangcheng ZHAO1, Jinsong DING1, 2, *
Affiliations
  • 1 Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, China
  • 2 Changsha King-eagle Medical Science and Technology Co., Ltd., Changsha 410013, China
Published: 2025-04-08 doi: 10.11669/cpj.2025.07.002
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Styrene-isoprene-styrene block copolymer pressure sensitive adhesive (SIS-PSA) is an ideal commercial adhesive with unique environmental attributes and high processability. As a key excipient for patches, SIS-PSA has a significant impact on the key properties such as drug release and adhesion. Since the performance of SIS-PSA is determined by a combination of different components, a thorough understanding of these components is essential for patch formulation design. This article discusses the impact of each component in SIS-PSA on the key performance of patches, summarizes the composition and application of marketed SIS-PSA patches, and focuses on patch formulation design oriented towards clinical needs, aiming to provide a reference for the research and development of SIS-PSA patches.

styrene-isoprene-styrene block copolymer  /  pressure sensitive adhesive  /  patch  /  adhesion property  /  formulation design
Difu SHI, Zhiyuan HOU, Xiangcheng ZHAO, Jinsong DING. Research Progress on SIS Pressure-Sensitive Adhesive: Functionality and Application in Patch Formulation Design[J]. Chinese Pharmaceutical Journal, 2025 , 60 (7) : 673 -679 . DOI: 10.11669/cpj.2025.07.002
Year 2025 volume 60 Issue 7
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doi: 10.11669/cpj.2025.07.002
  • Receive Date:2024-06-28
  • Online Date:2025-11-11
  • Published:2025-04-08
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  • Received:2024-06-28
Affiliations
    1 Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, China
    2 Changsha King-eagle Medical Science and Technology Co., Ltd., Changsha 410013, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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