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Advances in Targeted Delivery Carriers for Glycosylated Modified Materials
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Shangke YU1, Tuoping LI1, *, Weiqiao YANG2, *, Wenjuan WANG2, Xiaoliang DUAN2, Zhihang ZHANG3, Ruxia ZHAO4
Chinese Pharmaceutical Journal | 2025, 60(10) : 1005 - 1012
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Chinese Pharmaceutical Journal | 2025, 60(10): 1005-1012
Advances in Targeted Delivery Carriers for Glycosylated Modified Materials
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Shangke YU1, Tuoping LI1, *, Weiqiao YANG2, *, Wenjuan WANG2, Xiaoliang DUAN2, Zhihang ZHANG3, Ruxia ZHAO4
Affiliations
  • 1 Food Science College, Shenyang Agricultural University, Shenyang 110866, China
  • 2 Academy of National Food and Strategic Reserves Administration, Beijing 100037, China
  • 3 College of Food Science and Technology, Henan University of Technology, Zhengzhou 450001, China
  • 4 College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China
Published: 2025-05-01 doi: 10.11669/cpj.2025.10.001
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Glycans, as carriers of energy in the human body and important bioinformatic molecules, control the transmission of biological information through specific binding with proteins and other biomolecules. Taking advantage of this property, they have been used as targeted delivery ligands for designing and constructing glycosylation-modified targeted delivery systems, which provide new ideas for exploration and treatment in various fields such as antiviral, inhibition of pathogenic bacteria, and treatment of cancer. Compared with traditional drug therapy, glycosylation-modified targeted drug delivery systems have multiple advantages, such as high therapeutic efficiency, low drug usage, and lower toxic side effects, and have been a hot spot in the international frontiers of drug research and development in recent years. The authors summarize the current status of domestic and international research on glycosylated modified targeted delivery, and elaborate the research progress in the fields of anti-cancer drugs, antibacterial drugs, antiviral drugs, gene delivery, vaccine delivery, etc., which provides a reference to keep abreast of domestic and international research developments, and provides information support for the research and development of glycosylated modified material targeted delivery systems.

glycosylation  /  targeted delivery  /  anticancer drug  /  gene delivery
Shangke YU, Tuoping LI, Weiqiao YANG, Wenjuan WANG, Xiaoliang DUAN, Zhihang ZHANG, Ruxia ZHAO. Advances in Targeted Delivery Carriers for Glycosylated Modified Materials[J]. Chinese Pharmaceutical Journal, 2025 , 60 (10) : 1005 -1012 . DOI: 10.11669/cpj.2025.10.001
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Article Info
doi: 10.11669/cpj.2025.10.001
  • Receive Date：2024-08-29
  • Online Date：2025-11-09
  • Published：2025-05-01
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  • Received：2024-08-29
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Affiliations
    1 Food Science College, Shenyang Agricultural University, Shenyang 110866, China
    2 Academy of National Food and Strategic Reserves Administration, Beijing 100037, China
    3 College of Food Science and Technology, Henan University of Technology, Zhengzhou 450001, China
    4 College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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