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Research Progress on the Antidepressant Effect of Morinda officinalis Oligosaccharides
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Yongzhe SONG1, Jian ZHAO2, Xiao YE3, Min YU3, Xiaoru WU4, Beibei MA4, Tingting WANG4, Hairun YANG4, Wanhui LIU1, Xingchao GENG3, Zeping ZUO4, *, Ying LIU3, *
Chinese Pharmaceutical Journal | 2024, 59(10) : 872 - 878
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Chinese Pharmaceutical Journal | 2024, 59(10): 872-878
Research Progress on the Antidepressant Effect of Morinda officinalis Oligosaccharides
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Yongzhe SONG1, Jian ZHAO2, Xiao YE3, Min YU3, Xiaoru WU4, Beibei MA4, Tingting WANG4, Hairun YANG4, Wanhui LIU1, Xingchao GENG3, Zeping ZUO4, *, Ying LIU3, *
Affiliations
  • 1 Yantai University, Yantai 264003, China
  • 2 Center for Information, National Medical Products Administraiton, Beijing 100032, China
  • 3 National Institutes for Food and Drug Control, Beijing 102629, China
  • 4 Scientific Research Institute, Beijing Tongrentang Co., Ltd., Beijing 100079, China
Published: 2024-05-22 doi: 10.11669/cpj.2024.10.003
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Morinda officinalis is one of the four traditional southern medicines in China. Modern studies show that its oligosaccharides have good anti-depression activity.After continuous research and development by Chinese scientists, Morinda officinalis oligosaccharide Capsules, which are mainly composed of Morinda officinalis oligosaccharide, have been approved to be marketed as the fifth kinds of anti-depression new drugs in Chinese traditional medicine with independent intellectual property rights.By referring to the domestic and foreign literature on Morinda officinalis oligosaccharide as the research object, this paper comprehensively summarizes and combs the research and development process, anti-depression mechanism, extraction process, detection method and clinical application of Morinda officinalis oligosaccharide, which provides references for the subsequent research on Morinda officinalis oligosaccharides and the research and development of antidepressant drugs discovered from traditional Chinese medicine and natural products.

Morinda officinalis oligosaccharide  /  capsule  /  depression  /  clinical application  /  detection method
Yongzhe SONG, Jian ZHAO, Xiao YE, Min YU, Xiaoru WU, Beibei MA, Tingting WANG, Hairun YANG, Wanhui LIU, Xingchao GENG, Zeping ZUO, Ying LIU. Research Progress on the Antidepressant Effect of Morinda officinalis Oligosaccharides[J]. Chinese Pharmaceutical Journal, 2024 , 59 (10) : 872 -878 . DOI: 10.11669/cpj.2024.10.003
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doi: 10.11669/cpj.2024.10.003
  • Receive Date：2023-08-29
  • Online Date：2025-11-25
  • Published：2024-05-22
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  • Received：2023-08-29
Affiliations
    1 Yantai University, Yantai 264003, China
    2 Center for Information, National Medical Products Administraiton, Beijing 100032, China
    3 National Institutes for Food and Drug Control, Beijing 102629, China
    4 Scientific Research Institute, Beijing Tongrentang Co., Ltd., Beijing 100079, China
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https://castjournals.cast.org.cn/joweb/zgyxzz/EN/10.11669/cpj.2024.10.003
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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