Full
Outline
To observe the efficacy and safety of clindamycin hydrochloride palmitate dispersion tablets for the treatment of chronic periodontitis.
One hundred and fifty patients diagnosed with chronic periodontitis in our hospital from May 2020 to May 2021 were randomly divided into observation group (75 cases) and control group (75 cases). After the initial therapy of periodontal diseases, the two groups were administered with clindamycin hydrochloride palmitate dispersion tablets or cefaclor sustained-release capsules combined with metronidazole tablets for one week, respectively. Periodontal indexes, such as bleeding on probing (BOP), bleeding index (BI), periodontal probe depth (PD) and adhesion level (AL), as well as the total effective rate, incidence of adverse events and patient compliance, were observed and compared between the two groups.
Compared with the control group, the incidences of BOP and BI were significantly lower in the observation group after treatment (P<0.01), but PD and AL had no significant difference (P>0.05). The total effective rate of treatment in the observation group was lower than that of the control group, but the difference was not statistically significant (P>0.05). The incidence of adverse events in the observation group was lower than the control group and the patients had good compliance.
Clindamycin hydrochloride palmitate dispersion tablets was effective in the treatment of chronic periodontitis, with low incidence of adverse events, good safety and patient compliance.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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