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Comparison of the clinical application of Medium and Long Chain Fat Emulsion/Amino Acids/Glucose Injection with hospital-prepared all-in-one parenteral nutrient solution
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Qiu-lei XI1, Lun-xiu QIN2, Guo-qing TAO3, Zheng-jun QIU4, Ji-ren YU5, Guo-hao WU1
Chinese Journal of New Drugs | 2021, 30(18) : 1692 - 1697
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Chinese Journal of New Drugs | 2021, 30(18): 1692-1697
Comparison of the clinical application of Medium and Long Chain Fat Emulsion/Amino Acids/Glucose Injection with hospital-prepared all-in-one parenteral nutrient solution
Full
Qiu-lei XI1, Lun-xiu QIN2, Guo-qing TAO3, Zheng-jun QIU4, Ji-ren YU5, Guo-hao WU1
Affiliations
  • 1Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China
  • 2Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China
  • 3Wuxi People's Hospital, Wuxi 214043, China
  • 4Shanghai First People's Hospital, Shanghai 201620, China
  • 5The First Affiliated Hospital of Medical College of Zhejiang University, Hangzhou 310003, China
Published: 2021-09-30
Outline
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Objective:

To evaluate the efficacy and safety of Medium and Long Chain Fat Emulsion/Amino Acids (16)/Glucose (36%) Injection in nutritional therapy for patients receiving moderate or major abdominal surgery.

Methods:

Totally 240 cases of parenteral nutrition support patients receiving moderate or major abdominal surgery were enrolled in the randomized, double blind, multi-center, controlled study. The patients were randomized to be given Medium and Long Chain Fat Emulsion/Amino Acids (16)/Glucose (36%) Injection (n=122) or hospital-prepared all-in-one parenteral nutrient solution (n=118; nitrogen content, heat and liquid quantity as equal as the former) for 5 d. During the treatment process, the curative effect was observed, such as serum prealbumin (PA), retinol binding protein (RBP), hypersensitive C-reactive protein (hs-CRP) and IL-6; safety indicators such as weight, blood routine, blood biochemistry, urine routine, coagulation function, vital signs, electrocardiogram and adverse reactions of each system were monitored; the time spent for preparing the nutrient solution was calculated and the clinical efficacy was compared by statistical analysis.

Results:

There was no significant difference in efficacy and safety indicators between the two groups (P>0.05). However, the time spent for preparing the nutrient solution in the experimental group was significantly shorter than that in the control group (P<0.000 1).

Conclusion:

There is no significant difference in the curative effect and safety between the Medium and Long Chain Fat Emulsion/Amino Acids (16)/Glucose (36%) triple-chamber bag and the hospital-prepared all-in-one parenteral nutrient solution, but the former is more convenient to be prepared, which can save 13 minutes on average compared with the latter.

parenteral nutrition  /  medium and long chain fat emulsion/amino acids/glucose  /  industrialized triple-chamber bag
奚秋磊, 钦伦秀, 陶国清, 裘正军, 于吉人, 吴国豪. 中长链脂肪乳氨基酸葡萄糖三腔袋与院内配制全合一肠外营养液临床应用比较. 中国新药杂志, 2021 , 30 (18) : 1692 -1697 .
Qiu-lei XI, Lun-xiu QIN, Guo-qing TAO, Zheng-jun QIU, Ji-ren YU, Guo-hao WU. Comparison of the clinical application of Medium and Long Chain Fat Emulsion/Amino Acids/Glucose Injection with hospital-prepared all-in-one parenteral nutrient solution[J]. Chinese Journal of New Drugs, 2021 , 30 (18) : 1692 -1697 .
Year 2021 volume 30 Issue 18
32
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Article Info
  • Online Date:2026-10-30
  • Published:2021-09-30
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History
  • Accepted:2021-06-10
Funding
Affiliations
    1Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China
    2Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China
    3Wuxi People's Hospital, Wuxi 214043, China
    4Shanghai First People's Hospital, Shanghai 201620, China
    5The First Affiliated Hospital of Medical College of Zhejiang University, Hangzhou 310003, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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