To evaluate the efficacy and safety of Medium and Long Chain Fat Emulsion/Amino Acids (16)/Glucose (36%) Injection in nutritional therapy for patients receiving moderate or major abdominal surgery.
Totally 240 cases of parenteral nutrition support patients receiving moderate or major abdominal surgery were enrolled in the randomized, double blind, multi-center, controlled study. The patients were randomized to be given Medium and Long Chain Fat Emulsion/Amino Acids (16)/Glucose (36%) Injection (n=122) or hospital-prepared all-in-one parenteral nutrient solution (n=118; nitrogen content, heat and liquid quantity as equal as the former) for 5 d. During the treatment process, the curative effect was observed, such as serum prealbumin (PA), retinol binding protein (RBP), hypersensitive C-reactive protein (hs-CRP) and IL-6; safety indicators such as weight, blood routine, blood biochemistry, urine routine, coagulation function, vital signs, electrocardiogram and adverse reactions of each system were monitored; the time spent for preparing the nutrient solution was calculated and the clinical efficacy was compared by statistical analysis.
There was no significant difference in efficacy and safety indicators between the two groups (P>0.05). However, the time spent for preparing the nutrient solution in the experimental group was significantly shorter than that in the control group (P<0.000 1).
There is no significant difference in the curative effect and safety between the Medium and Long Chain Fat Emulsion/Amino Acids (16)/Glucose (36%) triple-chamber bag and the hospital-prepared all-in-one parenteral nutrient solution, but the former is more convenient to be prepared, which can save 13 minutes on average compared with the latter.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |