Full
Outline
Zeolitic imidazolate framework-8 (ZIF-8) is a metal organic framework composed of zinc ions and 2-methylimidazole (MIM). It exhibits unique advantages, such as easiness to synthesize, large surface area, high porosity, pH responsiveness, as well as excellent thermal stability and biocompatibility, due to all these properties, it is widely used in gas adsorption, catalysis and sensing. In recent years, research on ZIF-8 as a drug carrier has gradually increased, and it has been applied in anticancer drugs, antibacterial drugs, and hypoglycemic drugs, etc. This review focuses on the recent development of ZIF-8 synthesis methods and its application in chemical drugs, natural drugs, and biotechnology drug delivery systems, and analyzes the advantages and application characteristics of ZIF-8 in different types of drug delivery systems, in order to provide a reference for further research of ZIF-8 to deliver drugs.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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