Acorus calamus was first published in “Shen Nong's Materia Medica”. It is a traditional Chinese medicine for resuscitation and is widely used in prescriptions for the treatment of closed syndrome. In view of the exact clinical efficacy of calamus and the continuous discovery of new pharmacological activities and effective ingredients, in recent years, it has attracted wide attention in China and abroad and has become one of the hot research Chinese medicine varieties. However, the current edition of “Chinese Pharmacopoeia” stipulates the traditional physical and chemical identification of calamus and the determination of the total content of volatile oil. It is still difficult to reflect and directly relate the characteristics of calamus's multiple clinical functions with multiple complex components. The current quality markers of traditional Chinese medicine have pointed out the development direction and research ideas for the establishment of quality standards in line with the characteristics of traditional Chinese medicine. This article summarizes and analyzes the chemical components and pharmacological effects of calamus by consulting literature, and based on the definition of quality markers: The “five elements” of validity, uniqueness, transmission and traceability, measurability and prescription compatibility are used to predict and analyze the quality markers of calamus. The literature review found that the volatile components of Acorus calamus, especially the asarone components, can be used as the quality markers of this drug, providing a scientific basis for its complete quality control.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |