COVID-19 has been becoming popular all over the worldwide. As a coronavirus, both SARS-CoV-2 and SARS-CoV invade host cells through ACE2 receptor. Facing the extremely severe epidemic situation of COVID-19, there is a lack of vaccine and specific antiviral drug for this virus at present. Clinically, supportive treatment and symptomatic treatment are still the main measures. The roles of COVID-19 and ACE2 in SARS-CoV-2 were briefly introduced in this article. The results of the latest clinical trials of potential anti-COVID-19 drugs and the possible mechanisms of action of related drugs were summarized, in order to fully understand the development process of COVID-19 and direction of drug research thus to provide ideas for further study of COVID-19 drug therapy and vaccine development.

COVID-19  /  SARS-CoV-2  /  latest clinical research progress  /  therapeutic drug  /  mechanism of action