Full
Outline
To assess the general patterns and characteristics of adverse drug reactions (ADRs) induced by new antitumor drugs and provide reference for clinical medicination.
A total of 54 cases of ADR induced by new antitumor drugs were collected from January 2015 to December 2019 in Bengbu Adverse Drug Reaction Center, and analyzed statistically.
In the 54 ADR cases, male patients were more than females. The majority of the patients with ADR were over the age of 51 (n=45, 83.3%). The ADR cases were related to 15 kinds of new antitumor drugs, of which the drug rituximab was the one that caused the most ADR. The main consequences of these ADR cases involved following damages: skin and its accessories damage (19.8%) and digestive system damage (17.3%).
New antitumor drugs have been widely used in clinical. Clinicians and pharmacists should reinforce the monitoring on its using to ensure the safe and effective clinical application of new antitumor drugs.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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