Full
Outline
To construct a multidimensional value assessment framework for novel drugs for lung cancer, thereby supporting evidence-informed decision-making for medical insurance reimbursement.
First, literature on the value assessment of novel drugs for lung cancer was searched and reviewed. Based on a literature review and a focus group discussion, the framework was preliminarily constructed. Then, the Delphi method was used to determine the criteria, sub-criteria, weights, and value assessment methods. Finally, the feasibility of framework was verified through the value assessment of three novel drugs for lung cancer.
The constructed multidimensional value assessment framework for novel drugs for lung cancer consists of five core criteria, two contextualized criteria, and 20 sub-criteria. The core criteria include comparative effectiveness, comparative safety, affordability, economic value, and evidence quality, with comparative effectiveness having the highest weight. Among the sub-criteria of the core criteria, overall survival and progression-free survival have the highest weights. The contextual criteria are innovation and equity.
The structured multidimensional value assessment framework provides a decision-support tool for medical insurance policymakers and helps to improve the scientific rigor and transparency of decision-making.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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