Full
Outline
To compare the difference of medical resource utilization in intra-abdominal infectious patients administered with latamoxef, third-generation cephalosporins, β-lactamase inhibitor compound preparations and carbapenems, and help clinicians improve their treatment strategies.
Based on data from Hospital Information System, a 1∶1 non-replacement propensity score matching (PSM) method was performed to match participants with similar propensity scores between different groups, and the matched participants were adopted to compare their difference in medical resource utilization.
A total of 4 433 patients were included in this study. 292 pairs of patients administered with latamoxef or third-generation cephalosporins were matched by PSM. The average cost of antibiotics in the latamoxef group was 1 498.6 yuan higher than that in the third-generation cephalosporins group (P<0.05). 303 pairs of patients administered with latamoxef or β-lactamase inhibitor compound preparations were matched by PSM. Compared with the β-lactamase inhibitor compound preparations group, the average cost of hospitalization was 12 250.9 yuan lower and the average duration of hospitalization was 2.6 days shorter in the latamoxef group (P<0.05). 256 pairs of patients administered with latamoxef or carbapenems were matched by PSM. Compared with the carbapenems group, the average cost of antibiotics was 1 470.4 yuan lower, the average cost of hospitalization was 33210.9 yuan lower, the average duration of hospitalization was 6.1 days shorter and the mean ICU days was 1.4 days shorter in the latamoxef group (P<0.05).
In terms of treating intra-abdominal infection, patients administered with latamoxef showed less medical resource utilization when compared with those with β-lactamase inhibitor compound preparations and carbapenems, and they showed relatively similar medical resource utilization when compared to those with third-generation cephalosporins.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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