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A comparative study of real-world evidence and randomized controlled trial evidence
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Yu ZHANG1, 2, Yi QU1, 2, Li DONG1, 2, Ling-quan MENG1, 2, Zhe HUANG1, 2, Yu-wen CHEN1, 2
Chinese Journal of New Drugs | 2021, 30(11) : 971 - 975
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Chinese Journal of New Drugs | 2021, 30(11): 971-975
A comparative study of real-world evidence and randomized controlled trial evidence
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Yu ZHANG1, 2, Yi QU1, 2, Li DONG1, 2, Ling-quan MENG1, 2, Zhe HUANG1, 2, Yu-wen CHEN1, 2
Affiliations
  • 1Shenyang Pharmaceutical University School of Business Administration, Shenyang 110016, China
  • 2Shenyang Pharmaceutical University Shenyang Pharmaceutical University/Institute of Pharmaceutical Regulatory Sciences, Shenyang 110016, China
Published: 2021-06-15
Outline
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Results from large-sample double-blind randomized controlled trial (RCT) have always represented the highest level of evidence-based medicine clinical evidence, but it cannot solve all the clinical research problems, thus real-world evidence (RWE) based on the perspective of real-world research (RWS) has developed rapidly. This paper aims to provide reference for the further application and development of RWE by comparing the differences between RWE and randomized controlled trial evidence in data source, internal and external effectiveness, evidence level, application scope, experiment design, implementation elements and implementation cost.

real world data  /  real world evidence  /  randomized controlled trial evidence
张喻, 曲艺, 董丽, 孟令全, 黄哲, 陈玉文. 真实世界证据与随机对照试验证据比较研究. 中国新药杂志, 2021 , 30 (11) : 971 -975 .
Yu ZHANG, Yi QU, Li DONG, Ling-quan MENG, Zhe HUANG, Yu-wen CHEN. A comparative study of real-world evidence and randomized controlled trial evidence[J]. Chinese Journal of New Drugs, 2021 , 30 (11) : 971 -975 .
Year 2021 volume 30 Issue 11
37
8
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  • Online Date:2026-10-28
  • Published:2021-06-15
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  • Accepted:2020-11-29
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    1Shenyang Pharmaceutical University School of Business Administration, Shenyang 110016, China
    2Shenyang Pharmaceutical University Shenyang Pharmaceutical University/Institute of Pharmaceutical Regulatory Sciences, Shenyang 110016, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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