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New progress in research on drugs for treatment of hyperuricemia
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Qi-meng ZHOU, Xiao-yue ZHAO, Yu LIANG, De-wen KONG, Sen ZHANG, Wen ZHANG, Jun-ke SONG, Guan-hua DU
Chinese Journal of New Drugs | 2021, 30(10) : 929 - 936
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Chinese Journal of New Drugs | 2021, 30(10): 929-936
New progress in research on drugs for treatment of hyperuricemia
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Qi-meng ZHOU, Xiao-yue ZHAO, Yu LIANG, De-wen KONG, Sen ZHANG, Wen ZHANG, Jun-ke SONG, Guan-hua DU
Affiliations
  • Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2021-05-30
Outline
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Hyperuricemia results from excessive production of uric acid and/or physical excretion deficiency and is the core to formation and development of gout, which has caught attention of researchers due to increasing prevalence. The drugs currently used in clinic can control the development of gout, but still have various deficiencies. The hot spot of drugs under research is urate anion exchanger 1 (URAT1) inhibitor, but new conditions for old drug aiming at other targets are also worthy of attention. This article reviewed the progress in research on therapeutic drugs of hyperuricemia, aiming to provide reference for the development of new drugs.

hyperuricemia  /  gout  /  drug development  /  urate anion exchanger 1 inhibitor  /  new condition for old drug
周启蒙, 赵晓悦, 梁宇, 孔德文, 张森, 张雯, 宋俊科, 杜冠华. 治疗高尿酸血症相关药物研究新进展. 中国新药杂志, 2021 , 30 (10) : 929 -936 .
Qi-meng ZHOU, Xiao-yue ZHAO, Yu LIANG, De-wen KONG, Sen ZHANG, Wen ZHANG, Jun-ke SONG, Guan-hua DU. New progress in research on drugs for treatment of hyperuricemia[J]. Chinese Journal of New Drugs, 2021 , 30 (10) : 929 -936 .
Year 2021 volume 30 Issue 10
43
11
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  • Online Date:2026-10-28
  • Published:2021-05-30
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  • Accepted:2020-08-01
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    Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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