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Progress in evaluation and development of drugs for treatment of pulmonary fibrosis
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Long DENG1, 2, 3, Xiao-qing ZOU1, De-jian JIANG2
Chinese Journal of New Drugs | 2021, 30(8) : 712 - 717
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Chinese Journal of New Drugs | 2021, 30(8): 712-717
Progress in evaluation and development of drugs for treatment of pulmonary fibrosis
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Long DENG1, 2, 3, Xiao-qing ZOU1, De-jian JIANG2
Affiliations
  • 1College of Chemistry, Xiangtan University, Xiangtan 411105, China
  • 2Hunan Research Center for Safety Evaluation of Drugs, Hunan Key Laboratory of Pharmacodynamics and Safety Evaluation of New Drugs, Changsha 410331, China
  • 3High Tech Research Institute, Guangdong University of Petrochemical Technology, Maoming 525000, China
Published: 2021-04-30
Outline
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Pulmonary fibrosis (PF) is an advancing and fatal lung disease with increasing incidence and prevalence, which is one of the leading causes of death from lung diseases. This article summarizes the recent advances in disease pathogenesis, animal models, drugs under investigation and therapeutic targets, aiming to provide new ideas for developing drugs to treat pulmonary fibrosis.

pulmonary fibrosis  /  animal models  /  drug development
邓龙, 邹晓青, 姜德建. 治疗肺纤维化药物的评价与开发进展. 中国新药杂志, 2021 , 30 (8) : 712 -717 .
Long DENG, Xiao-qing ZOU, De-jian JIANG. Progress in evaluation and development of drugs for treatment of pulmonary fibrosis[J]. Chinese Journal of New Drugs, 2021 , 30 (8) : 712 -717 .
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Year 2021 volume 30 Issue 8
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  • Online Date：2026-10-28
  • Published：2021-04-30
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History
  • Accepted：2020-09-29
Affiliations
    1College of Chemistry, Xiangtan University, Xiangtan 411105, China
    2Hunan Research Center for Safety Evaluation of Drugs, Hunan Key Laboratory of Pharmacodynamics and Safety Evaluation of New Drugs, Changsha 410331, China
    3High Tech Research Institute, Guangdong University of Petrochemical Technology, Maoming 525000, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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