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Exploration on extraction processes of compound Ruyi Jinhuang Powder based on orthogonal design and multi-index weight analysis
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Ya-li ZHAO, Si-qi ZHANG, Wen-xi LU, Chong CHEN, Li WEI
Chinese Journal of New Drugs | 2021, 30(15) : 1428 - 1434
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Chinese Journal of New Drugs | 2021, 30(15): 1428-1434
Exploration on extraction processes of compound Ruyi Jinhuang Powder based on orthogonal design and multi-index weight analysis
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Ya-li ZHAO, Si-qi ZHANG, Wen-xi LU, Chong CHEN, Li WEI
Affiliations
  • Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Published: 2021-08-15
Outline
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Objective:

To determine the index weight, optimize the extraction process of compound Ruyi Jinhuang Powder, and to provide a reference for its further research and developmemt of industrial production.

Methods:

Taking the extraction capacity of curcumin, berberine hydrochloride, aloe-emodin, magnolol and extract yield as comprehensive evaluation indexes, the weighting coefficient in 5 synthetic evaluation indexes was determined by analytic hierarchy process (AHP), criteria importance through intercriteria correlation (CRITIC) method, and mixed weighted AHP-CRITIC. Combined with the results of orthogonal test, the extraction process parameters of Ruyi Jinhuang Powder were optimized.

Results:

Compared with AHP method and CRITIC method, AHP-CRITIC mixed weighting method was more scientific, reasonable and stable. The optimal process parameters were confirmed as decocting for 3 times with 2.0 h each adding 8 times volume of the amount of 75% ethanol.

Conclusion:

The weight coefficient determined by AHP-CRITIC mixed weighting method was objective and real, which can reflect the compatibility information of compound Ruyi Jinhuang Powder. The optimized extraction process was stable and feasible with good repeatability, providing reference for industrial production.

Ruyi Jinhuang Powder  /  extraction process  /  orthogonal experiment  /  AHP method  /  CRITICAL method  /  AHP-CRITIC mixed weighting method
赵亚丽, 张斯琪, 鲁文茜, 陈冲, 魏莉. 基于多指标权重分析和正交设计法优选如意金黄散复方提取工艺. 中国新药杂志, 2021 , 30 (15) : 1428 -1434 .
Ya-li ZHAO, Si-qi ZHANG, Wen-xi LU, Chong CHEN, Li WEI. Exploration on extraction processes of compound Ruyi Jinhuang Powder based on orthogonal design and multi-index weight analysis[J]. Chinese Journal of New Drugs, 2021 , 30 (15) : 1428 -1434 .
Year 2021 volume 30 Issue 15
44
10
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  • Online Date:2026-10-28
  • Published:2021-08-15
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  • Accepted:2021-01-13
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    Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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