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Progress in researches on photoimmunoconjugates
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Ying-ju XU1, Yu-ming SONG2, Hai-bin LU1
Chinese Journal of New Drugs | 2021, 30(16) : 1471 - 1476
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Chinese Journal of New Drugs | 2021, 30(16): 1471-1476
Progress in researches on photoimmunoconjugates
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Ying-ju XU1, Yu-ming SONG2, Hai-bin LU1
Affiliations
  • 1Jilin University College of Pharmacy, Changchun 130031, China
  • 2Jilin University Department of Respiratory Medicine, China-Japan Friendship Hospital, Changchun 130031, China
Published: 2021-08-30
Outline
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In recent years, the incidence of malignant tumors has been increasing. After conventional treatments such as surgical resection, chemotherapy, and radiotherapy, many patients' conditions are still not effectively controlled. Therefore, exploring new treatment methods has become the focus of tumor prevention and control. The role of photoimmunotherapy (PIT) in solid tumor research is becoming more and more prominent. Photoimmunoconjugate (PIC) has the ability of tumor-specific recognition and high cytotoxicity. This article reviews the progress in the development of such novel molecular targeted drugs in the past decade, and the results from the study of using porphyrin, chlorin e6 (Ce6), phthalocyanine dye (IR700) and other photosensitizer conjugated monoclonal antibodies (MAbs) as photosensitizing drugs were discussed respectively.

photoimmunotherapy  /  photosensitizer  /  monoclonal antibodies  /  photoimmunoconjugates
徐颖菊, 宋玉明, 路海滨. 光免疫偶联物的研究进展. 中国新药杂志, 2021 , 30 (16) : 1471 -1476 .
Ying-ju XU, Yu-ming SONG, Hai-bin LU. Progress in researches on photoimmunoconjugates[J]. Chinese Journal of New Drugs, 2021 , 30 (16) : 1471 -1476 .
Year 2021 volume 30 Issue 16
38
8
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  • Online Date:2026-10-28
  • Published:2021-08-30
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  • Accepted:2020-12-07
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    1Jilin University College of Pharmacy, Changchun 130031, China
    2Jilin University Department of Respiratory Medicine, China-Japan Friendship Hospital, Changchun 130031, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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