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Outline
As a new drug carrier, albumin nanoparticles have many characteristics, such as biodegradability, biocompatibility, non-toxicity and non-immunogenicity, and it has shown unique tumor targeting mechanism. Most of anti-tumor drugs are water-insoluble, poor drugability of preparation, and of high adverse reaction. For the purpose of changing its physical and chemical properties and reducing the adverse effects, albumin nanoparticles are often applied as carrier to deliver anti-tumor drug. The surface modification of albumin nanoparticles and coating of plasma membrane greatly enhance the drug targeting, improve the solubility, reduce the toxicity, prolong in vivo circulation, and even enhance the efficacy of drugs. In this paper, the preparation process and surface modification of albumin nanoparticles are reviewed in order to provide reference for the study of related drugs of albumin nanoparticles.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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