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The role of exosomal miRNAs in depression and progress in research on it as biomarker
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Yu-hui CHAI1, Ya-wen CAI1, Ming-xing MIAO2, Tian-hua YAN1
Chinese Journal of New Drugs | 2021, 30(16) : 1466 - 1470
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Chinese Journal of New Drugs | 2021, 30(16): 1466-1470
The role of exosomal miRNAs in depression and progress in research on it as biomarker
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Yu-hui CHAI1, Ya-wen CAI1, Ming-xing MIAO2, Tian-hua YAN1
Affiliations
  • 1China Pharmaceutical University Department of Physiology and Pharmacology, College of Basic Medicine and Clinical Pharmacy, Nanjing 210009, China
  • 2China Pharmaceutical University National Pharmacy Experimental Teaching Demonstration Center, Nanjing 210009, China
Published: 2021-08-30
Outline
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Depression is a type of mental illness that seriously endangers the physical and mental health of humans. The clinical manifestations are marked and lasting symptoms such as depressed mood, low mood, slow thinking and other symptoms. However, its pathogenesis and the therapeutic target is still unclear. Exosomes are lipid bilayer cystic vesicles carrying biological information molecules such as lipids, proteins, DNA, and miRNAs, which mediate information transmission between cells and regulate the expression of related signal pathways. At present, the study of exosomal miRNAs in depression is relatively extensive, providing new application prospects for early diagnosis and treatment of depression. In this paper, we mainly reviewed the latest research progress in exosomal miRNAs in depression.

depression  /  exosomes  /  miRNA  /  mechanism  /  biomarker
柴玉慧, 蔡雅文, 缪明星, 颜天华. 外泌体miRNAs在抑郁症中的作用及作为其生物标志物的研究进展. 中国新药杂志, 2021 , 30 (16) : 1466 -1470 .
Yu-hui CHAI, Ya-wen CAI, Ming-xing MIAO, Tian-hua YAN. The role of exosomal miRNAs in depression and progress in research on it as biomarker[J]. Chinese Journal of New Drugs, 2021 , 30 (16) : 1466 -1470 .
Year 2021 volume 30 Issue 16
33
8
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  • Online Date:2026-10-28
  • Published:2021-08-30
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  • Accepted:2020-11-18
Affiliations
    1China Pharmaceutical University Department of Physiology and Pharmacology, College of Basic Medicine and Clinical Pharmacy, Nanjing 210009, China
    2China Pharmaceutical University National Pharmacy Experimental Teaching Demonstration Center, Nanjing 210009, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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