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This paper analyzed the situation of patent applications of anti-tumor traditional Chinese medicine (TCM) in China in order to provide suggestions for the research, development, utilization and innovation of anti-tumor TCM. The Patentics patent database was used as the data source to search and analyze the patent application of anti-tumor TCM in China. The patent applications of anti-tumor TCM in China mainly experienced three stages: steady development (2000—2012), rapid outbreak (2013—2015) and slowing down (2016-present). However, the quality of patent applications showed an opposite trend, resulting in a low patent effective rate (21%). The quality of the patents applied by modern pharmaceutical enterprises and universities showed a higher level. The patent applications of pharmaceutical enterprises mainly focused on the extract of TCM and preparation process, while universities mainly focused on TCM composition and compound preparations. In an overall view, the patent application quality of anti-tumor TCM in China is relatively low, we should improve the patent quality, learn from the foreign patent layout experience, enhance the ability of university-enterprise collaborative innovation, and promote the inheritance and development of TCM.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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