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Evaluation of the performance of one kind of imported nitrofurantoin susceptibility test disk
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Ge ZHANG1, 2, Jing-jing HUANG1, 2, 3, Si-meng DUAN1, 2, Jing-jia ZHANG1, 2, Ying ZHAO1, 2, Chun-ying XU1, 2
Chinese Journal of New Drugs | 2021, 30(22) : 2111 - 2115
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Chinese Journal of New Drugs | 2021, 30(22): 2111-2115
Evaluation of the performance of one kind of imported nitrofurantoin susceptibility test disk
Full
Ge ZHANG1, 2, Jing-jing HUANG1, 2, 3, Si-meng DUAN1, 2, Jing-jia ZHANG1, 2, Ying ZHAO1, 2, Chun-ying XU1, 2
Affiliations
  • 1Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
  • 2Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing 100730, China
  • 3Graduate School, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China
Published: 2021-11-30
Outline
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Objective:

To evaluate the detection performance of one kind of imported nitrofurantoin susceptibility test disk for antimicrobial susceptibility test by disk diffusion method.

Methods:

A total of 118 strains of pathogenic bacteria were collected from a Class A tertiary comprehensive hospital in Beijing from 2016 to 2017, including 61 isolates of Enterobacterales, 48 isolates of Staphylococcus spp. and 9 isolates of Enterococcus spp. Antimicrobial susceptibility test was performed following Clinical and Laboratory Standards Institute (CLSI) documents M100ED30, using disk diffusion method. The differences of susceptibility between domestic disks and imported disks against 118 bacteria strains were detected according to the breakpoints described in CLSI documents M100ED30. The rate of categorical agreement (CA) of susceptibility conducted by the two kinds of disks was calculated.

Results:

Among the 118 isolates, 73, 4 and 41 were categorized as susceptible (S), intermediate (I), and resistant (R) to nitrofurantoin, respectively. The rate of categorical agreement of susceptibility to nitrofurantoin using imported disks and domestic disks was 100%.

Conclusion:

The results of susceptibility test using imported nitrofurantoin disks are reliable, and consistent with the results by domestic nitrofurantoin disks. Imported nitrofurantoin disk can meet the requirements of clinical laboratory. The test results will provide direct reference data for clinical application for nitrofurantoin in infectious diseases.

nitrofurantoin  /  disk diffusion method  /  urinary tract infection
张戈, 黄晶晶, 段思蒙, 张京家, 赵颖, 徐春英. 一种进口呋喃妥因药敏纸片试验性能评价. 中国新药杂志, 2021 , 30 (22) : 2111 -2115 .
Ge ZHANG, Jing-jing HUANG, Si-meng DUAN, Jing-jia ZHANG, Ying ZHAO, Chun-ying XU. Evaluation of the performance of one kind of imported nitrofurantoin susceptibility test disk[J]. Chinese Journal of New Drugs, 2021 , 30 (22) : 2111 -2115 .
Year 2021 volume 30 Issue 22
55
9
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  • Online Date:2026-10-28
  • Published:2021-11-30
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  • Accepted:2021-08-07
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Affiliations
    1Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
    2Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing 100730, China
    3Graduate School, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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