To evaluate the efficacy and safety of chamomile tablets in the treatment of pediatric otolaryngological diseases and explore its clinical application characteristics.
A retrospective analysis was conducted on medical records of children aged 1~14 years who were prescribed chamomile tablets at multiple hospitals in Guangdong Province and Xinjiang Uygur Autonomous Region between October 2015 and October 2024. Data including demographic information, clinical diagnoses, medication details (dosage, frequency, and duration), changes in clinical symptoms before and after treatment, and relevant laboratory test results were collected. Statistical analysis was performed using SAS 9.4 software.
A total of 7 485 patients were included, with school-aged and preschool-aged children accounting for 83.7% of the cohort. Xiangju Tablets were primarily used for the treatment of pediatric allergic rhinitis (3 075 cases), pediatric sinusitis (1 291 cases), chronic tonsillitis and adenoid-related diseases (997 cases), as well as chronic rhinitis, nasopharyngitis, and pharyngitis (1 836 cases). The most common regimen was 1~2 tablets administered three times daily. The combination use rate of Xiangju Tablets reached 96.77%, and it is often combined with antihistamines and corticosteroids to enhance therapeutic efficacy. Laboratory findings indicated improvements in liver function and immune parameters. No serious adverse events were observed during the study period.
Xiangju Tablets demonstrate favorable efficacy in the treatment of pediatric otolaryngological diseases. Overall, this drug exhibits a good safety profile and represent an effective therapeutic option for children with otolaryngological conditions, showing promising clinical potential. However, the current data are insufficient to fully confirm its independent efficacy and specific role in combination therapy, and its clinical application value still needs to be further verified by higher-quality studies.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |