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Key points and considerations of clinical study design for medication timing
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Xiang-yi ZHENG1, Gen-ming ZHANG1, Zi-yu TIAN2, Ying GAO1, 3, Xin-xing LAI1, 3, *
Chinese Journal of New Drugs | 2025, 34(17) : 1839 - 1844
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Chinese Journal of New Drugs | 2025, 34(17): 1839-1844
Key points and considerations of clinical study design for medication timing
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Xiang-yi ZHENG1, Gen-ming ZHANG1, Zi-yu TIAN2, Ying GAO1, 3, Xin-xing LAI1, 3, *
Affiliations
  • 1Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
  • 2Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China
  • 3Institute for Brain Disorders, Beijing University of Chinese Medicine, Beijing 100700, China
Published: 2025-09-15 doi: 10.20251/j.cnki.1003-3734.2025.17.008
Outline
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The medication timing is an important factor affecting the clinical efficacy of drugs. Selecting the right medication timing is the key to ensure the full play of drug efficacy, as well as standardized and precise medication practices in clinical settings. Although some scholars have carried out relevant clinical studies on the medication timing, there remains a lack of systematic review and summary of its important research significance and key points of scheme design. This paper systematically discusses the concept of medication timing, research significance, understanding of traditional Chinese medicine, types of research design and key methodological points, aiming to clarify the design ideas for clinical research on medication timing, and focus on analyzing the similarities and differences, as well as key design points of different types of clinical studies. This article provides methodological guidance for timely and precise medication in clinical practice and effectively promotes the standardization and accuracy of clinical drug use.

medication timing  /  timing of intervention  /  clinical research  /  scheme design  /  precision medication
Xiang-yi ZHENG, Gen-ming ZHANG, Zi-yu TIAN, Ying GAO, Xin-xing LAI. Key points and considerations of clinical study design for medication timing[J]. Chinese Journal of New Drugs, 2025 , 34 (17) : 1839 -1844 . DOI: 10.20251/j.cnki.1003-3734.2025.17.008
Year 2025 volume 34 Issue 17
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Article Info
doi: 10.20251/j.cnki.1003-3734.2025.17.008
  • Online Date:2026-03-06
  • Published:2025-09-15
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  • Accepted:2024-12-18
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Affiliations
    1Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
    2Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China
    3Institute for Brain Disorders, Beijing University of Chinese Medicine, Beijing 100700, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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