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Development of the 14th national reference standard for histamine phosphate
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Yuan ZHANG1, Long-jing GUO2, Ze-an YANG1, De-jiang TAN1, Yan-lin WU1, *
Chinese Journal of New Drugs | 2025, 34(17) : 1852 - 1857
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Chinese Journal of New Drugs | 2025, 34(17): 1852-1857
Development of the 14th national reference standard for histamine phosphate
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Yuan ZHANG1, Long-jing GUO2, Ze-an YANG1, De-jiang TAN1, Yan-lin WU1, *
Affiliations
  • 1National Institute for Food and Drug Control, Beijing 102629, China
  • 2Beiing Minhai Biotechnology Co., Ltd., Beiing 102609, China
Published: 2025-09-15 doi: 10.20251/j.cnki.1003-3734.2025.17.010
Outline
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Objective:

To establish the 14th batch of national reference standards for histamine phosphate.

Methods:

Histamine phosphate was identified using infrared spectroscopy and bioactivity assay. Its hygroscopicity, moisture content, and uniformity were also examined. Using the 13th batch of national reference standard for histamine phosphate as the standard, 4 laboratories were selected to conduct collaborative calibration of the potency of the reference standard using the cat blood pressure method.

Results:

The final combined potency of this batch of standard products was determined to be 97.8%.

Conclusion:

This batch of reference materials can be used as the 14th batch of national reference materials for histamine phosphate, with a relative potency set at 100%, batch numbers 150510-202214.

histamine phosphate  /  national reference standard  /  standard material determination value  /  depressor substance test
Yuan ZHANG, Long-jing GUO, Ze-an YANG, De-jiang TAN, Yan-lin WU. Development of the 14th national reference standard for histamine phosphate[J]. Chinese Journal of New Drugs, 2025 , 34 (17) : 1852 -1857 . DOI: 10.20251/j.cnki.1003-3734.2025.17.010
Year 2025 volume 34 Issue 17
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Article Info
doi: 10.20251/j.cnki.1003-3734.2025.17.010
  • Online Date:2026-03-06
  • Published:2025-09-15
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History
  • Accepted:2025-02-28
Affiliations
    1National Institute for Food and Drug Control, Beijing 102629, China
    2Beiing Minhai Biotechnology Co., Ltd., Beiing 102609, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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