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Advances in radioimmunotherapy targeting B7-H3
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Meng ZHENG1, 2, Yan WANG1, 2, Feng-qing FU3, 4, Li-yan MIAO1, 2
Chinese Journal of New Drugs | 2023, 32(7) : 687 - 694
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Chinese Journal of New Drugs | 2023, 32(7): 687-694
Advances in radioimmunotherapy targeting B7-H3
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Meng ZHENG1, 2, Yan WANG1, 2, Feng-qing FU3, 4, Li-yan MIAO1, 2
Affiliations
  • 1Clinical Pharmacology Research Laboratory, the First Affiliated Hospital of Suzhou University, Suzhou 215006, China
  • 2Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Suzhou University, Suzhou 215123, China
  • 3Institute of Clinical Immunology, the First Affiliated Hospital of Suzhou University, Suzhou 215006, China
  • 4State Key Laboratory of Radiation Medicine and Protection, Suzhou University, Suzhou 215123, China
Published: 2023-04-15
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Recently, radioimmunotherapy (RIT) has attracted much attention because of its precision targeted therapy. It is a therapeutic mode with great clinical application value to select an appropriate target molecule for radioimmunotherapy. B7-H3, also known as CD276, is an immune checkpoint molecule belonging to the B7 immunoglobin superfamily, which makes it an ideal candidate for RIT agents due to its unique expression characteristics and biological functions. Herein, we summarize the expression characteristics and biological functions of B7-H3. We also review the latest developments in radioimmunotherapy targeting B7-H3 in the context of cancer therapeutic.

B7-H3  /  CD276  /  radioimmunotherapy  /  targeted therapy  /  tumor
Meng ZHENG, Yan WANG, Feng-qing FU, Li-yan MIAO. Advances in radioimmunotherapy targeting B7-H3[J]. Chinese Journal of New Drugs, 2023 , 32 (7) : 687 -694 .
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Year 2023 volume 32 Issue 7
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  • Online Date：2026-03-06
  • Published：2023-04-15
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  • Accepted：2022-04-05
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Affiliations
    1Clinical Pharmacology Research Laboratory, the First Affiliated Hospital of Suzhou University, Suzhou 215006, China
    2Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Suzhou University, Suzhou 215123, China
    3Institute of Clinical Immunology, the First Affiliated Hospital of Suzhou University, Suzhou 215006, China
    4State Key Laboratory of Radiation Medicine and Protection, Suzhou University, Suzhou 215123, China
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表12种不同金属材料的力学参数
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Number of
genus		 种数
Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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