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Bcr-Abl inhibitors are targeted drugs for the treatment of chronic myeloid leukemia (CML). Due to the high selectivity with few side effects, some of them have become the first-line drugs in the treatment of CML. Therefore, Bcr-Abl inhibitors have become the hotspot of anti-CML drug research. Based on the patent publication records of Bcr-Abl inhibitors, this article analyzes the research and development trends of Bcr-Abl inhibitors from the publication time and regional distribution, compares and analyzes the research progress through technical topics, and finally selects an enterprise to analyze its subsequent patent application for drug research and development in China and abroad, in order to provide relevant reference for the research and development of Bcr-Abl inhibitors.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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