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Research progress in antitumor effects of 2-anilinoquinolines derivatives
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Feng-feng LI, Yi-hua GUO, Rong-dong LI
Chinese Journal of New Drugs | 2023, 32(8) : 817 - 825
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Chinese Journal of New Drugs | 2023, 32(8): 817-825
Research progress in antitumor effects of 2-anilinoquinolines derivatives
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Feng-feng LI, Yi-hua GUO, Rong-dong LI
Affiliations
  • Hunan University of Chinese Medicine, Changsha 410208, China
Published: 2023-04-30
Outline
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2-anilinoquinoline is a characteristic structure of anticancer drugs, which can regulate various molecular targets related to tumor proliferation, differentiation, migration and apoptosis. Studies found that modifying the C-3, C-4, C-5 positions on the 2-anilinoquinoline ring and the aminobenzene ring to connect them with different groups, such as alkoxy, amide, carbonyl etc., can improve the targeting effect of drugs and enhance cytotoxicity. This review focuses on the structural modification and research progress of 2-anilinoquinoline derivatives as antitumor drugs in recent years to provide reference for future research.

2-anilinoquinolines  /  anticancer activity  /  structure-activity relationship
Feng-feng LI, Yi-hua GUO, Rong-dong LI. Research progress in antitumor effects of 2-anilinoquinolines derivatives[J]. Chinese Journal of New Drugs, 2023 , 32 (8) : 817 -825 .
Year 2023 volume 32 Issue 8
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  • Online Date:2026-03-06
  • Published:2023-04-30
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  • Accepted:2022-04-12
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    Hunan University of Chinese Medicine, Changsha 410208, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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