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To analyze the effect of Wuzhi capsule on tacrolimus concentration and clinical efficacy.
The Chinese databases of Wanfang, CNKI and Weipu were searched to collect the relevant studies on the effect of Wuzhi capsule on the plasma concentration and clinical efficacy of tacrolimus in patients with nephrotic syndrome. The literatures that met the standards were included, and the effective data were extracted. SPSS 27.0 statistical software was applied for analysis.
A total of 4 studies were included, and the statistical analysis results showed that Wuzhi capsule improved the plasma concentration of tacrolimus and standardized plasma concentration, and the difference was statistically significant (P<0.05). The 24-hour urine protein level in drug combination group was lower than that in single drug group, and the plasma albumin level was higher.
Wuzhi capsule can significantly improve the plasma concentration of tacrolimus and clinical efficacy in patients with nephrotic syndrome.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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