PDF
Full
Outline
Small-cell lung cancer (SCLC) is one of the most malignant subtypes of lung cancer with rapid tumor progression and a poor prognosis, and also one of the malignancies most difficult to cure in clinical practice. Currently, platinum-based chemotherapy remains the first-line standard treatment for extensive-stage small cell lung cancer (ES-SCLC). Full-dose chemotherapy is warranted for the best efficacy, and the effective rate of first-line treatment is 60%~80% (full-dose), while chemotherapy-induced myelosuppression (CIM) is the main reason hindering adequate chemotherapy. Granulocyte colony-stimulating factor (G-CSF) is commonly used to deal with neutropenia in clinical practice, while this traditional treatment may even cause the depletion of bone marrow hematopoietic reserve function and damage to the normal bone marrow hematopoietic function of patients. Currently, trilaciclib has been approved for the prevention of myelosuppression in ES-SCLC, which can protect hematopoietic stem cells/progenitor cells (HSPCs) fundamentally. In this paper, we report a case of a patient with ES-SCLC treated in our department receiving bone marrow protection with trilaciclib combined with chemotherapy, aiming to provide reference and basis for further research.
PDF
36
15
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62199257
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
