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Research progress of biomimetic carrier of cancer cell membrane in tumor therapy
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Xin SONG1, 2, 3, Bo-hua XU2, Shu-zhe WANG2, Qiao-yu TAO1, 2, 3, Li-li FU1, 2, 3, Lu-yao SUN1, 2, 3, Yun-liang QIU4
Chinese Journal of New Drugs | 2023, 32(23) : 2403 - 2410
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Chinese Journal of New Drugs | 2023, 32(23): 2403-2410
Research progress of biomimetic carrier of cancer cell membrane in tumor therapy
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Xin SONG1, 2, 3, Bo-hua XU2, Shu-zhe WANG2, Qiao-yu TAO1, 2, 3, Li-li FU1, 2, 3, Lu-yao SUN1, 2, 3, Yun-liang QIU4
Affiliations
  • 1School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230013, China
  • 2InnoStar Bio-tech Nantong Co., Ltd., Nantong 226133, China
  • 3China Yangtze Delta Drug Advanced Research Institute, Nantong 226133, China
  • 4China State Institute of Pharmaceutical Industry, Shanghai InnorStar Biotech Co., Ltd., Shanghai 201203, China
Published: 2023-12-15
Outline
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Tumor therapy has always been the focus of study. Due to the variability of tumor cells, the complexity of the tumor microenvironment and other factors, the problems such as multidrug resistance of tumors, reduced drug delivery efficiency are obtained. In recent years, increasing attention has been paid to biomimetic vectors, in which cancer cell membrane (CCM) is a new type of nano-carrier with the characteristics of homologous targeting, immune escape and penetrating biological barrier. Using CCM as a bionic carrier to coat different types of nanoparticles (NPs) can achieve effective tumor targeting and advantages in tumor therapy. This review introduces the biomimetic vector of CCM, briefly describes the preparation process of NPs coated with CCM, summarizes the research of CCM in tumor drug delivery and tumor vaccine, and discusses the future development prospects of CCM.

biomimetic carriers  /  cancer cell membranes  /  nanoparticles  /  drug delivery  /  tumor vaccine
Xin SONG, Bo-hua XU, Shu-zhe WANG, Qiao-yu TAO, Li-li FU, Lu-yao SUN, Yun-liang QIU. Research progress of biomimetic carrier of cancer cell membrane in tumor therapy[J]. Chinese Journal of New Drugs, 2023 , 32 (23) : 2403 -2410 .
Year 2023 volume 32 Issue 23
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  • Online Date:2026-03-05
  • Published:2023-12-15
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  • Accepted:2023-04-12
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Affiliations
    1School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230013, China
    2InnoStar Bio-tech Nantong Co., Ltd., Nantong 226133, China
    3China Yangtze Delta Drug Advanced Research Institute, Nantong 226133, China
    4China State Institute of Pharmaceutical Industry, Shanghai InnorStar Biotech Co., Ltd., Shanghai 201203, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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