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Chemical constituents and pharmacological effects of Astragali Radix and predictive analysis on quality markers
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Yi-xuan ZHANG1, Hai-long LIU2, Rui-qiong WANG1, 3, Qian-qian MA1, Min FANG1, Quan-yang LI1, Guo-tai WU1, 3
Chinese Journal of New Drugs | 2023, 32(4) : 410 - 419
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Chinese Journal of New Drugs | 2023, 32(4): 410-419
Chemical constituents and pharmacological effects of Astragali Radix and predictive analysis on quality markers
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Yi-xuan ZHANG1, Hai-long LIU2, Rui-qiong WANG1, 3, Qian-qian MA1, Min FANG1, Quan-yang LI1, Guo-tai WU1, 3
Affiliations
  • 1Gansu University of Chinese Medicine, Lanzhou 730000, China
  • 2Gansu Province Traditional Chinese Medicine Modern Pharmaceutical Engineering Research Institute Co., Ltd., Lanzhou 730010, China
  • 3Gansu Province Key Laboratory of Pharmacology and Toxicology of Traditional Chinese Medicine, Lanzhou 730000, China
Published: 2023-02-28
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Huangqi (Astragali Radix) is the dry root of Mongol Milkvetch (Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao) and Membranous Milkvetch (Astragalus membranaceus (Fisch.) Bge.), which is a major medicinal material in Gansu Province. It mainly contains Astragali Radix polysaccharides, flavonoids, saponins, alkaloids, amino acids, trace elements, organic acids and other chemical components. The pharmacological effects of Huangqi mainly focus on improving immunity, anti-oxidation, anti-tumor, protecting cardiovascular, promoting body metabolism, lowering blood sugar, diuresis and decreasing swelling. Based on literature retrieval, the distribution of resources, chemical components and pharmacological effects of Astragalus are reviewed and summarized. The quality markers (Q-Marker) of Astragali Radix are predicted based on traditional medicinal properties, efficacy, chemical components and different compatibility. The chemical components of Astragali Radix polysaccharide, ononin, calycosin, formononetin, astragaloside Ⅰ, astragaloside Ⅱ, and astragaloside Ⅳ were predicted by the analysis, providing a scientific basis for the quality control of Astragali Radix.

Astragali Radix  /  quality marker  /  chemical compositions  /  pharmacological  /  immunomodulatory
Yi-xuan ZHANG, Hai-long LIU, Rui-qiong WANG, Qian-qian MA, Min FANG, Quan-yang LI, Guo-tai WU. Chemical constituents and pharmacological effects of Astragali Radix and predictive analysis on quality markers[J]. Chinese Journal of New Drugs, 2023 , 32 (4) : 410 -419 .
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  • Online Date：2026-03-05
  • Published：2023-02-28
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  • Accepted：2022-07-18
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    1Gansu University of Chinese Medicine, Lanzhou 730000, China
    2Gansu Province Traditional Chinese Medicine Modern Pharmaceutical Engineering Research Institute Co., Ltd., Lanzhou 730010, China
    3Gansu Province Key Laboratory of Pharmacology and Toxicology of Traditional Chinese Medicine, Lanzhou 730000, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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