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Characteristics of charged aerosol detector and its application in pharmaceutical analysis
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Xue-song WU1, 2, Yong-sheng LEI1, 2, 3, Mu-jun ZHANG1, 2, 3, Wei CHEN1, 2, Yi PAN1, 2, Hua CHEN1
Chinese Journal of New Drugs | 2023, 32(4) : 420 - 427
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Chinese Journal of New Drugs | 2023, 32(4): 420-427
Characteristics of charged aerosol detector and its application in pharmaceutical analysis
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Xue-song WU1, 2, Yong-sheng LEI1, 2, 3, Mu-jun ZHANG1, 2, 3, Wei CHEN1, 2, Yi PAN1, 2, Hua CHEN1
Affiliations
  • 1Tianjin Institute of Pharmaceutical Research Co., Ltd., Tianjin 300462, China
  • 2Technology R&D Center of Tianjin Taipu Pharmaceutical Co., Ltd., Tianjin 300462, China
  • 3Research Unit for Drug Metabolism, Chinese Academy of Medical Sciences, Tianjin 300450, China
Published: 2023-02-28
Outline
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Charged aerosol detector (CAD) is a new universal liquid chromatography detector rapidly developed in recent years. It has the advantages of high sensitivity, broad linear range, the signal response consistency independent of chemical structures, as well as the feature of simple operation. It is especially suitable for detecting substances without ultraviolet absorption. This paper briefly summarizes the working principle and detection characteristics of CAD detector and its application in the analysis fields of traditional Chinese medicine and natural products, chemical drugs, sugars, biochemical drugs, pharmaceutic adjuvant and surfactants, so as to provide reference for its better application in the liquid chromatographic analysis.

charged aerosol detector  /  characteristics  /  pharmaceutical analysis  /  application
Xue-song WU, Yong-sheng LEI, Mu-jun ZHANG, Wei CHEN, Yi PAN, Hua CHEN. Characteristics of charged aerosol detector and its application in pharmaceutical analysis[J]. Chinese Journal of New Drugs, 2023 , 32 (4) : 420 -427 .
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Year 2023 volume 32 Issue 4
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  • Online Date：2026-03-05
  • Published：2023-02-28
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History
  • Accepted：2022-07-18
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Affiliations
    1Tianjin Institute of Pharmaceutical Research Co., Ltd., Tianjin 300462, China
    2Technology R&D Center of Tianjin Taipu Pharmaceutical Co., Ltd., Tianjin 300462, China
    3Research Unit for Drug Metabolism, Chinese Academy of Medical Sciences, Tianjin 300450, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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