Taste masking is one of the key issues to improve drug compliance in children during the development of oral liquid preparations of traditional Chinese medicine (TCM). Because different families of TCM contain different odors, and TCMs are generally used as compound preparations in clinical practice, the taste usually presents a complex blend phenomenon. At present, the main methods to improve the taste of TCM oral liquids are medicinal materials processing, pre-treatment, preparation technology modification, adding auxiliary materials and so on. but the masking effect and application range of various masking methods are different. In practical application, the masking methods should be selected according to the drug type, dosage form and equipment needs. This paper summarizes the classification, application and new taste masking technology of TCM oral liquid preparations for children by sorting and analyzing relevant journals and patents, so as to provide reference for the research on this kind of pharmaceutical preparations.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |