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Infection is a great challenge that threatens human health today. The immune system consists of cells, tissues, and molecules in the body that work together to protect against foreign pathogens, such as infections, to maintain health. Infection triggers an immune response, but dysfunction of T cells, B cells and NK cells has the potential to predispose patients to infection and reduce the clearance or suppression of pathogenic microorganisms. Since interleukin-2 (IL-2) has been shown to stimulate and up-regulate the function and number of CD4+ T cells and CD8+ T cells, it has been widely reported that IL-2 can increase anti-infective function and clinical efficacy in the treatment of a variety of chronic infectious diseases. This article reviews the possible mechanism of IL-2 in infection immunity and related clinical trials, aiming to provide a reference for the prevention and treatment of chronic infectious diseases with low dose of IL-2.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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