PDF
Full
Outline
Non-alcoholic steatohepatitis (NASH) has a global prevalnce of about 3%~5%, and lifestyle interventions are the main prevention and treatment methods of NASH. The diet pill orlistat, antioxidant vitamin E, and insulin sensitizer pioglitazone have certain therapeutic effects on NASH. In recent years, many therapeutic drugs for NASH of different mechanisms have entered clinical trials at different stages, such as the double agonist lanifibranor of peroxisome proliferator activated receptor α/δ, glucagon-like peptide-1 receptor agonist liraglutide, acetyl CoA carboxylase inhibitor firsocostat, thyroid hormone receptor agonist resmetirom, stearyl-CoA desaturase-1 inhibitor aramchol, sodium-glucose cotransporter 2 inhibitor dapagliflozin, fibroblast growth factor-21 analogue efruxifermin, Fani-X receptor agonist obeticholic acid, etc. In this paper, the current status of NASH treatment and clinical research of new drugs are systematically summarized.
PDF
41
9
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62199257
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
