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Research and development of new vitiligo drugs: challenges and prospects
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Cong MA1, Jin-ping YUAN2, Xing-hua GAO1, Yan WU1
Chinese Journal of New Drugs | 2023, 32(19) : 1972 - 1978
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Chinese Journal of New Drugs | 2023, 32(19): 1972-1978
Research and development of new vitiligo drugs: challenges and prospects
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Cong MA1, Jin-ping YUAN2, Xing-hua GAO1, Yan WU1
Affiliations
  • 1Department of Dermatology, First Affiliated Hospital of China Medical University, Shenyang 110000, China
  • 2Department of Dermatology, Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
Published: 2023-10-15
Outline
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Vitiligo is a kind of refractory depigmentation skin disease, which seriously affects the appearance and psychology of patients. At present, the pathogenesis of vitiligo includes heredity, oxidative stress, autoimmunity and environmental factors. The treatment includes systematic application of glucocorticoid, local application of glucocorticoid or calcineurin inhibitor, phototherapy and melanocyte transplantation. In this article, we reviewed the commonly used therapeutic drugs for vitiligo in the past and summarized the new progress of therapeutic drugs for the treatment of vitiligo. The emergence of new small-molecule targeted drugs, such as Janus kinase inhibitor baricitinib, has brought hope for vitiligo.

vitiligo  /  new drugs development  /  Janus kinase inhibitor
Cong MA, Jin-ping YUAN, Xing-hua GAO, Yan WU. Research and development of new vitiligo drugs: challenges and prospects[J]. Chinese Journal of New Drugs, 2023 , 32 (19) : 1972 -1978 .
Year 2023 volume 32 Issue 19
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Article Info
  • Online Date:2026-03-05
  • Published:2023-10-15
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  • Accepted:2023-07-03
Affiliations
    1Department of Dermatology, First Affiliated Hospital of China Medical University, Shenyang 110000, China
    2Department of Dermatology, Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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