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Since the reform of the drug review and approval system, with the support of a series of policies and technology that encourages innovation, a large number of clinical trial application of new drugs for skin disease has been approved. In addition, innovative drugs, high-quality generic drugs, and biosimilar products have been accelerately approved, which meets the availability and accessibility of drugs to a certain extent. In order to guide innovation and scientific development of new drugs for skin disease, this article reviews the reform of drug review and approval system, the continuous improvement of the drug regulatory system, and the progress in development, evaluation and approval of new drugs for skin disease in China. We focus on the challenges, opportunities, and improvement measures faced in the development, evaluation, and regulation of drugs in this field. With multiple measures simultaneously taken, the goal is to meet the urgent clinical medication needs of patients with skin disease, so that effective and safe drugs can benefit patients as soon as possible.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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