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Outline
Shenge Bushen Capsule is a traditional Chinese medicine (TCM) compound preparation developed under the guidance of TCM theory and combined with modern pharmaceutical technology. It is indicated for mild to moderate depression of TCM syndrome of qi and yin deficiency, and kidney qi deficiency. Based on a summary of the chemical constituents of Shenge Bushen Capsule, this study applied network pharmacology methods and integrated the core concept of quality marker (Q-Marker) to predict and analyze the Q-Marker of Shenge Bushen Capsule. The results showed that formononetin, 3'-methoxydaidzein, daidzein-4,7-diglucoside, puerarin, icariin, anhydroicaritin, chrysoseriol, kaempferol, luteolin, and quercetin are the key active components of Shenge Bushen Capsules and can serve as its Q-Marker. Which can provide a reference for establishing a comprehensive quality standard for Shenge Bushen Capsule.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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