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Application of ion chromatography in pharmaceutical analysis
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Yong-xiang LIU1, 2, 3, Xiao YE2, 3, Bin LI1, 2, 3, Yun-li ZHAO1, *, Ye TIAN2, 3, *
Chinese Journal of New Drugs | 2026, 35(9) : 942 - 950
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Chinese Journal of New Drugs | 2026, 35(9): 942-950
Application of ion chromatography in pharmaceutical analysis
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Yong-xiang LIU1, 2, 3, Xiao YE2, 3, Bin LI1, 2, 3, Yun-li ZHAO1, *, Ye TIAN2, 3, *
Affiliations
  • 1Shenyang Pharmaceutical University, Shenyang 110016, China
  • 2Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing 100176, China
  • 3State Key Laboratory of Drug Regulatory Science, Beijing 102629, China
Published: 2026-05-15 doi: 10.20251/j.cnki.1003-3734.2026.09.007
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Ion chromatography, an important branch of liquid chromatography, has been widely used in the field of analytical chemistry due to its advantages including rapidity, sensitivity, good selectivity, and the ability to simultaneously determine multiple components. This paper comprehensively summarizes the technical principles, development history, detection methods and pretreatment techniques of ion chromatography (IC), with emphasis on its application in pharmaceutical analysis, particularly in the quality control of aminoglycoside antibiotics, with the aim of providing a comprehensive summary for future research and application.

ion chromatography  /  amperometry detector  /  conductance detector  /  aminoglycosides  /  pharmaceutical analysis
刘永祥, 叶潇, 李彬, 赵云丽, 田冶. 离子色谱技术在药物分析中的应用. 中国新药杂志, 2026 , 35 (9) : 942 -950 . DOI: 10.20251/j.cnki.1003-3734.2026.09.007
Yong-xiang LIU, Xiao YE, Bin LI, Yun-li ZHAO, Ye TIAN. Application of ion chromatography in pharmaceutical analysis[J]. Chinese Journal of New Drugs, 2026 , 35 (9) : 942 -950 . DOI: 10.20251/j.cnki.1003-3734.2026.09.007
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Year 2026 volume 35 Issue 9
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Article Info
doi: 10.20251/j.cnki.1003-3734.2026.09.007
  • Online Date：2026-10-26
  • Published：2026-05-15
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  • Accepted：2025-11-25
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Affiliations
    1Shenyang Pharmaceutical University, Shenyang 110016, China
    2Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing 100176, China
    3State Key Laboratory of Drug Regulatory Science, Beijing 102629, China
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表12种不同金属材料的力学参数
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Family		 属数
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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