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Research progress in effects of benzodiazepines on prognosis of tumor patients
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Yan LIU1, 2, Ying-bin WANG2, Li ZHANG1, 2, Lu CAO1, 2, Wei ZHANG1, 2, Xin-fang LI1, 2, Jia GUO1, 2, Jing-yu ZHANG2
Chinese Journal of New Drugs and Clinical Remedies | 2024, 43(5) : 321 - 326
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Chinese Journal of New Drugs and Clinical Remedies | 2024, 43(5): 321-326
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Research progress in effects of benzodiazepines on prognosis of tumor patients
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Yan LIU1, 2, Ying-bin WANG2, Li ZHANG1, 2, Lu CAO1, 2, Wei ZHANG1, 2, Xin-fang LI1, 2, Jia GUO1, 2, Jing-yu ZHANG2
Affiliations
  • 1.The Second Clinical Medical College of Lanzhou University, Lanzhou GANSU 730000, China
  • 2.Department of Anesthesiology, Second Hospital of Lanzhou University, Lanzhou GANSU 730030, China
Published: 2024-05-25 doi: 10.14109/j.cnki.xyylc.2024.05.01
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There are many factors affecting the prognosis of tumor patients, and the related mechanisms are still unclear, among which anesthetics also have certain influence on the prognosis of tumor patients. Benzodiazepines are widely used in surgical anesthesia for tumor patients due to their sedative properties. Previous studies have found that diazepam and midazolam can inhibit the proliferation of tumor cells and induce apoptosis or necrosis. In addition, midazolam can also stabilize the perioperative state of patients, improve the efficacy of chemotherapy drugs, and thus improve the prognosis of patients. Remimazolam can improve the prognosis of tumor patients by alleviating intraoperative stress and immunosuppression. The direct effect of remimazolam on the prognosis of these tumor patients and the related mechanisms need to be further explored.

benzodiazepines  /  neoplasms  /  diazepam  /  midazolam  /  remimazolam
Yan LIU, Ying-bin WANG, Li ZHANG, Lu CAO, Wei ZHANG, Xin-fang LI, Jia GUO, Jing-yu ZHANG. Research progress in effects of benzodiazepines on prognosis of tumor patients[J]. Chinese Journal of New Drugs and Clinical Remedies, 2024 , 43 (5) : 321 -326 . DOI: 10.14109/j.cnki.xyylc.2024.05.01
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Year 2024 volume 43 Issue 5
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Article Info
doi: 10.14109/j.cnki.xyylc.2024.05.01
  • Receive Date：2022-11-25
  • Online Date：2026-03-20
  • Published：2024-05-25
Article Data
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History
  • Received：2022-11-25
  • Accepted：2023-12-19
Funding
Affiliations
    1.The Second Clinical Medical College of Lanzhou University, Lanzhou GANSU 730000, China
    2.Department of Anesthesiology, Second Hospital of Lanzhou University, Lanzhou GANSU 730030, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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