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Signaling pathways such as PI3K/AKT/mTOR, Hippo/YAP, Notch, Wnt/β-catenin, and TGF-β play the critical role in the malignant biological behaviors of triple-negative breast cancer（TNBC）, including proliferation, invasion,metastasis, and drug resistance. However, conventional chemotherapy drugs often lead to severe adverse reactions, and the utilization of nanotechnology presents a promising solution to this issue. Nano-drug delivery system based on inhibiting signal transduction pathways can carry conventional chemotherapy drugs, block the proliferation of cancer cells, and impede the progression of TNBC. This approach not only offers advantages in targeted therapy but also reduces tissue damage significantly, giving patients more benefits in the future.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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