Home Journals Articles Updates About
CN
image
收藏切换
Clinical Efficacy of the Chinese Medicine Compound Rulikang in the Treatment of Bovine Mastitis
收藏切换
PDF
Ziqi TAO1, Arsebek Jumamamat1, Yali LI2, Chao GONG1, Bo WANG1, Wanhe LUO3, Yakup Omar1, Zhihui HAO1, 4, Yan SUN5, Juncheng HAN1, *, Xiaohua DAI1, *
China Dairy | 2026, (5) : 71 - 78
Less
收藏切换
China Dairy | 2026, (5): 71-78
• DISEASE PREVENTION •
Clinical Efficacy of the Chinese Medicine Compound Rulikang in the Treatment of Bovine Mastitis
Full
Ziqi TAO1, Arsebek Jumamamat1, Yali LI2, Chao GONG1, Bo WANG1, Wanhe LUO3, Yakup Omar1, Zhihui HAO1, 4, Yan SUN5, Juncheng HAN1, *, Xiaohua DAI1, *
Affiliations
  • 1.Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous AnimaIs (XJ-LNDRDHA)), College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi Xinjiang 830052
  • 2.College of Animal Science and Technology, Xinjiang Agricultural Vocational and Technical University, Changji Xinjiang 831100
  • 3.College of Animal Science and Technology, Tarim University, Animal Disease Diagnosis, Prevention and Control Engineering Laboratory, Alar Xinjiang 843300
  • 4.College of Veterinary Medicine, China Agricultural University, Beijing 100193
  • 5.Xinjiang Nongmu Investment Group Haozi Animal Husbandry Co., Ltd., Changji Xinjiang 831100
Published: 2026-05-25 doi: 10.12377/1671-4393.26.05.11
Outline
收藏切换
[Objective]

This study aimed to verify the antibacterial effect and clinical efficacy of Chinese Medicine Compound Rulikang against pathogenic bacteria of bovine mastitis.

[Method]

Chinese Medicine Compound Rulikang, consisting of Taraxacum mongolicum, Forsythia suspensa, Akebia quinata, Vaccaria segetalis and Astragalus membranaceus, was prepared into liquid with a crude drug concentration of 1 g/mL by water decoction and concentration. Escherichia coli, Staphylococcus aureus and Streptococcus agalactiae isolated from clinical bovine mastitis cases were used to assess its in vitro antibacterial activity. Thirty bovines suffering from clinical mastitis were assigned into low, medium and high dose groups, while 10 healthy bovines were set as the control group. Intramammary perfusion was performed twice a day for 7 consecutive days. The clinical efficacy and variations of milk protein indicators were observed.

[Result]

Chinese Medicine Compound Rulikang exhibited strong inhibitory effects on the three pathogenic strains. After 7 days of treatment, the effective rate and cure rate of the high dose group reached 88.2% (15/17) and 82.4% (14/17), respectively. Milk yield of all administration groups was higher than that of the control group. The levels of SA, ALT, AST and LDH in cow whey decreased significantly (P<0.05), whereas lactose content barely changed.

[Conclusion]

Chinese Medicine Compound Rulikang had prominent therapeutic effects on clinical bovine mastitis, which provided a safe and effective herbal preparation for the disease treatment.

Chinese Medicine Compound Rulikang  /  bovine mastitis  /  in vitro bacteriostasis  /  clinical efficacy
Ziqi TAO, Arsebek Jumamamat, Yali LI, Chao GONG, Bo WANG, Wanhe LUO, Yakup Omar, Zhihui HAO, Yan SUN, Juncheng HAN, Xiaohua DAI. Clinical Efficacy of the Chinese Medicine Compound Rulikang in the Treatment of Bovine Mastitis[J]. China Dairy, 2026 , (5) : 71 -78 . DOI: 10.12377/1671-4393.26.05.11
Appendix
Less
Year 2026 volume Issue 5
PDF
117
16
Cite this Article
BibTeX
Article Info
doi: 10.12377/1671-4393.26.05.11
  • Online Date：2026-08-20
  • Published：2026-05-25
Article Data
Affiliations
History
Funding
Affiliations
    1.Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous AnimaIs (XJ-LNDRDHA)), College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi Xinjiang 830052
    2.College of Animal Science and Technology, Xinjiang Agricultural Vocational and Technical University, Changji Xinjiang 831100
    3.College of Animal Science and Technology, Tarim University, Animal Disease Diagnosis, Prevention and Control Engineering Laboratory, Alar Xinjiang 843300
    4.College of Veterinary Medicine, China Agricultural University, Beijing 100193
    5.Xinjiang Nongmu Investment Group Haozi Animal Husbandry Co., Ltd., Changji Xinjiang 831100
References
Share
https://castjournals.cast.org.cn/joweb/zgry/EN/10.12377/1671-4393.26.05.11
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House